NNC 687 manufacturers
- ADX-10061
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- $2500.00
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2026-04-21
- CAS:128022-68-4
- Purity:
- Supply Ability: 10g
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| | NNC 687 Basic information |
| Product Name: | NNC 687 | | Synonyms: | NNC 687;ADX10061;CEE-03-310;CEE-310;NNC-01-0687;ADX10061,ADX 10061;ADX-10061 | | CAS: | 128022-68-4 | | MF: | C19H20N2O4 | | MW: | 340.37 | | EINECS: | | | Product Categories: | | | Mol File: | 128022-68-4.mol |  |
| | NNC 687 Chemical Properties |
| Boiling point | 477.305±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.311±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 6.775±0.40(predicted) |
| | NNC 687 Usage And Synthesis |
| Uses | ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia[1]. | | IC 50 | D1 Receptor: 5.8 nM (Ki); D2 Receptor: > >10 000 nM (Ki) | | References | [1] Andersen PH, et al. NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists. Eur J Pharmacol. 1992;219(1):45-52. DOI:10.1016/0014-2999(92)90578-r |
| | NNC 687 Preparation Products And Raw materials |
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