| Company Name: |
Energy Chemical |
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | avarone Basic information |
| Product Name: | avarone | | Synonyms: | avarone;2-[[(1R)-1,2,3,4,4a,7,8,8aα-Octahydro-1,2β,4aβ,5-tetramethylnaphthalen-1-yl]methyl]-2,5-cyclohexadiene-1,4-dione;2-[[(1R)-1,2β,4aβ,5-Tetramethyl-1,2,3,4,4a,7,8,8aα-octahydronaphthalene-1α-yl]methyl]-1,4-benzoquinone;2,5-Cyclohexadiene-1,4-dione, 2-[[(1R,2S,4aS,8aS)-1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl]methyl]-;(+)-Avarone | | CAS: | 55303-99-6 | | MF: | C21H28O2 | | MW: | 312.45 | | EINECS: | | | Product Categories: | | | Mol File: | 55303-99-6.mol |  |
| | avarone Chemical Properties |
| Melting point | 61-63 °C(Solv: hexane (110-54-3); ethyl ether (60-29-7)) | | Boiling point | 402.9±20.0 °C(Predicted) | | density | 1.039±0.06 g/cm3(Predicted) | | form | Brown oil. |
| | avarone Usage And Synthesis |
| Uses | Avarone is a cystostatic agent which displays antibacterial and antifungal activities. Also, it is derived from 2-Methoxybenzenemethanol (M260760), which is used in the synthesis of antimycobacterial and antibacterial derivatives. Also used in the synthesis of phthalazines and analogues as benzodiazepine receptos ligands with specific activity. | | in vivo | Avarone (10 mg/kg; i.p.; once daily for 5 days) shows increases life span of leukemic mice[2]. | Animal Model: | 8-9 months, 32-35 g Male outbred NMIR mice (L5178Y cells)[2] | | Dosage: | 10 mg/kg | | Administration: | I.p.; once daily for 5 days | | Result: | Increased life span over controls by 146% when treatment was begun 1 day after tumor implantation and by 87% when treatment was delayed until day 8. |
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| | avarone Preparation Products And Raw materials |
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