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1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated

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1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated Basic information
Product Name:1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated
Synonyms:1-(1,1-dimethylethyl)-2-methoxy-4-methyl-benzen nitrated;1-(1,1-dimethylethyl)-2-methoxy-4-methyl-benzennitrated;1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated;Musk aMbrette paste;2-Methoxy-4-methyl-1-(2-methyl-2-propanyl)-3,5-dinitrobenzene;1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated USP/EP/BP;TIAFNU-CHEM 1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated 73507-41-2;Musk ambrette
CAS:73507-41-2
MF:C12H16N2O5
MW:268.26584
EINECS:
Product Categories:
Mol File:73507-41-2.mol
1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated Structure
1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated Chemical Properties
Melting point 83°C
OdorSweet, yet heavy, floral-musky odor
Water Solubility Almost insoluble in water
EPA Substance Registry SystemBenzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl-, nitrated (73507-41-2)
Safety Information
TSCA TSCA listed
toxicityThe acute oral LD50 in rats has been reported as 339 mg/kg (Jenner, Hagan, Taylor, Cook & Fitzhugh, 1964) and as 4.8 g/kg (4.3-5.3 g/kg) (Moreno, 1972a). The acute dermal LD50 in rabbits exceeded 2 g/kg (Moreno, 1972b)
MSDS Information
1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated Usage And Synthesis
DescriptionMusk ambrette is a pale yellowish or whitish-yellow or yellow crystal (varying with crystal size and structure). Almost insoluble in water, 3.3% soluble in alcohol, 37% soluble in Diethyl phthalate, 50% soluble in Benzyl benzoate, practically insoluble in Terpenes or mineral oil. The sweet, yet heavy, floral-musky odor of excellent tenacity. The characteristic note of this Nitromusk is the floral tone of its muskiness.
Chemical PropertiesLight yellow crystal. Melting point 84-86 ℃, soluble in 95% ethanol 3.3%, benzyl benzoate 50%, benzyl alcohol 29%. There is a heavy sweet animal aroma and ambergris, musk, musk sunflower oil breath, vaguely with floral and aniseed rhyme, the aroma is quite long, bitter taste.
OccurrenceHas apparently not been reported to occur in nature
UsesMusk Ambrette is one of the most frequently used artificial musks. It is hard to imagine a day's work unless the jar with Musk Ambrette has been used. Musk Ambrette is used to a minor degree in flavor compositions. It finds its way into such types as Cherry, Maple, Nut, Spice, Vanilla, Mint, Fruit, etc., and has been used in trace amounts in dentifrice flavors.
PreparationBy nitration of the corresponding benzene derivative (Bedoukian, 1967).
DefinitionChEBI: Musk ambrette is a C-nitro compound.
1-(1,1-Dimethylethyl)-2-methoxy-4-methylbenzene nitrated Preparation Products And Raw materials
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