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2-nitro-4-Bromo-5-fluorobenzoic acid

2-nitro-4-Bromo-5-fluorobenzoic acid Suppliers list
Company Name: Hebei Chuanghai Biotechnology Co., Ltd
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Products Intro: Product Name:2-nitro-4-Bromo-5-fluorobenzoic acid
CAS:1020717-99-0
Purity:99% Package:1KG;0.00;USD|25KG;0.00;USD
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Products Intro: Product Name:2-Nitro-4-Bromo-5-fluorobenzoic acid
CAS:1020717-99-0
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: Product Name:2-Nitro-4-Bromo-5-fluorobenzoic acid
CAS:1020717-99-0
Purity:0.98 Package:25KG;5KG;1KG Remarks:Mature product
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Products Intro: Product Name:2-nitro-4-Bromo-5-fluorobenzoic acid
CAS:1020717-99-0
Purity:99% Package:1KG;1USD
Company Name: Changzhou Ansciep Chemical Co., Ltd.
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Products Intro: Product Name:4-Bromo-5-fluoro-2-nitrobenzoic acid
CAS:1020717-99-0
Purity:0.99 Package:100g, 500g, 1kg, 25kg, 50kg, 200kg Remarks:Good quality; Large stock; Hot sale

2-nitro-4-Bromo-5-fluorobenzoic acid manufacturers

2-nitro-4-Bromo-5-fluorobenzoic acid Basic information
Product Name:2-nitro-4-Bromo-5-fluorobenzoic acid
Synonyms:2-nitro-4-Bromo-5-fluorobenzoic acid;4-Bromo-5-fL;uoro-2-nitrobenzoic acid;Benzoic acid, 4-bromo-5-fluoro-2-nitro-;4-Bromo-5-fluoro-2-nitrobenzoicacid,98%;CAS:1020717-99-0
CAS:1020717-99-0
MF:C7H3BrFNO4
MW:264.01
EINECS:
Product Categories:
Mol File:1020717-99-0.mol
2-nitro-4-Bromo-5-fluorobenzoic acid Structure
2-nitro-4-Bromo-5-fluorobenzoic acid Chemical Properties
Boiling point 367.6±42.0 °C(Predicted)
density 1.967±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka1.68±0.25(Predicted)
form crystalline powder
color Off-white
Safety Information
HS Code 2916399090
MSDS Information
2-nitro-4-Bromo-5-fluorobenzoic acid Usage And Synthesis
Uses 2-nitro-4-Bromo-5-fluorobenzoic acid is an important intermediate for the synthesis of a new generation of fluoroquinolone drugs represented by ciprofloxacin.
Synthesis 2,4-Dibromo-5-fluorotoluene was brominated with NBS, hydrolyzed in acid to form aldehyde, and then oxidized by Jones reagent to obtain 2-nitro-4-Bromo-5-fluorobenzoic acid.
References[1] Patent: CN106146482, 2016, A. Location in patent: Paragraph 0124; 0125; 0126
[2] Patent: WO2017/98440, 2017, A1. Location in patent: Page/Page column 113
[3] Patent: WO2014/128655, 2014, A1. Location in patent: Page/Page column 20
[4] Patent: WO2015/17589, 2015, A1. Location in patent: Page/Page column 42
[5] Patent: US2015/183802, 2015, A1. Location in patent: Paragraph 1175-177
2-nitro-4-Bromo-5-fluorobenzoic acid Preparation Products And Raw materials
Raw materials4-Bromo-3-fluorobenzoic acid
Preparation Products2-amino-4-bromo-5-fluorobenzoicacidhydrochloride
Tag:2-nitro-4-Bromo-5-fluorobenzoic acid(1020717-99-0) Related Product Information

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