3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)-

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3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)- Basic information
Product Name:3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)-
Synonyms:3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)-
CAS:161923-56-4
MF:C42H80NO9P
MW:774.06
EINECS:
Product Categories:
Mol File:161923-56-4.mol
3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)- Structure
3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)- Chemical Properties
solubility Ethanol: Slightly Soluble: 0.1-1 mg/ml
Safety Information
MSDS Information
3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)- Usage And Synthesis
Uses1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC (13-HODE-PC) is an oxidized phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HODE (HY-113884B) at the sn-1 and sn-2 positions, respectively. 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC has the ability to compete for the binding of 125I-NO2-LDL (5 g/mL) to CD36-transfected 293 cells, with the IC50 of ＞ 200 μM[1].
References[1] Eugene A Podrez, et al. Identification of a Novel Family of Oxidized Phospholipids That Serve as Ligands for the Macrophage Scavenger Receptor CD36. J Biol Chem. 2002 Oct 11;277(41):38503-16. DOI:10.1074/jbc.M203318200
[2] BAO Y.P.  Williamson G  Chambers S J. Direct Separation of Hydroperoxy- and Hydroxy-Phosphatidylcholine Derivatives: Application to the Assay of Phospholipid Hydroperoxide Glutathione Peroxidase[J]. Analytical biochemistry, 1995, 224 1: Pages 395-399. DOI: 10.1006/abio.1995.1056
3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)- Preparation Products And Raw materials
Tag:3,5,8-Trioxa-4-phosphahexacosa-17,19-dien-1-aminium, 4,21-dihydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide, (7R,17Z,19E,21S)-(161923-56-4) Related Product Information
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC 1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC 1-Palmitoyl-2-(±)17(18)-EpETE-sn-glycero-3-PC 1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PC Acetic acid, 2-[4-[3-[4-(dimethylamino)phenyl]-3-oxo-1-propen-1-yl]-2-methoxyphenoxy]-