STL001

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STL001 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
STL001 Basic information
Product Name:STL001
Synonyms:STL001;2-Furancarboxylic acid, 3-[1-[4-(4-morpholinyl)-6-(phenylamino)-1,3,5-triazin-2-yl]-1H-pyrazol-3-yl]phenyl ester;RMA-4087
CAS:3047493-70-6
MF:C27H23N7O4
MW:509.52
EINECS:
Product Categories:
Mol File:3047493-70-6.mol
STL001 Structure
STL001 Chemical Properties
Boiling point 775.997±70.00 °C(Press: 760.00 Torr)(predicted)
density 1.426±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka4.154±0.10(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
STL001 Usage And Synthesis
UsesSTL001 is potent and selective FOXM1 inhibitor. STL001 induces the translocation of nuclear FOXM1 to the cytoplasm and promotes its autophagic degradation. STL001 sensitizes human cancers to a broad-spectrum of cancer therapies[1].
References[1] Sanjeev Raghuwanshi, et al. Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies. Cell Death Discov. 2024 May 2;10(1):211. DOI:10.1038/s41420-024-01929-0
STL001 Preparation Products And Raw materials
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