| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
- TRIPALMITIN
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- $1.00
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2019-07-06
- CAS:555-44-2
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100KG
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| | Tripalmitin Basic information |
| Product Name: | Tripalmitin | | Synonyms: | TRIPALMITIN(RG);Glyceryl tripalmitate,Glycerol tripalmitate, Tripalmitin;Tripalmitin 100mg [555-44-2];TRIHEXADECANOIN;TRIPALMITIN;1,2,3-propanetriyltri(hexadecanoate);1,2,3-tris-hexadecanoyloxy-propane;2,3-Bis(palmitoyloxy)propyl palmitate | | CAS: | 555-44-2 | | MF: | C51H98O6 | | MW: | 807.32 | | EINECS: | 209-098-1 | | Product Categories: | Fatty Acid Derivatives & Lipids;Glycerols | | Mol File: | 555-44-2.mol |  |
| | Tripalmitin Chemical Properties |
| Melting point | 66-68 °C | | Boiling point | bp 310-320° | | density | 0.8752 g/cm3 (70 ºC) | | refractive index | nD80 1.43807 | | storage temp. | -20°C | | solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Hexanes (Very Slightly) | | form | Fine Crystalline Powder | | color | White to almost white | | biological source | synthetic (organic) | | Merck | 14,9736 | | BRN | 1811188 | | Cosmetics Ingredients Functions | SKIN CONDITIONING
VISCOSITY CONTROLLING | | InChIKey | PVNIQBQSYATKKL-UHFFFAOYSA-N | | SMILES | CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC | | LogP | 21.615 (est) | | CAS DataBase Reference | 555-44-2(CAS DataBase Reference) | | EPA Substance Registry System | Tripalmitin (555-44-2) |
| Hazard Codes | Xn | | Risk Statements | 20/22 | | Safety Statements | 22-24/25 | | WGK Germany | - | | RTECS | RT4953500 | | TSCA | TSCA listed | | HS Code | 29157090 | | Storage Class | 11 - Combustible Solids |
| | Tripalmitin Usage And Synthesis |
| Description | Tripalmitin, also known as Palmitin or 1,2,3-Tripalmitoyl glycerol, comes from the fatty acid palmitic acid and is a triacylglycerol that contains palmitic acid at the sn-1, sn-2, and sn-3 positions and has been found in palm oil. It inhibits glucose-stimulated insulin secretion and reduces viability of INS1 cells in a concentration-dependent manner. Myocardial levels of 1,2,3-tripalmitoyl glycerol are elevated by greater than 5-fold in a rat model of diabetes induced by streptozotocin . 1,2,3-Tripalmitoyl glycerol has been used to form the lipid matrices of etoposide-incorporated nanoparticles. Formulations containing 1,2,3-tripalmitoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents. | | Chemical Properties | White, crystalline powder. Soluble in ether and chloroform;
insoluble in water. Combustible. | | Uses | Tripalmitin is a triglyceride derived from Palmitic Acid (P144500), a common fatty acid found in plants and animals. Tripalmitin is used in the preparation of solid lipid particles for oral delivery of drugs. | | Uses | Soap, leather dressing. | | Uses |
Glyceryl tripalmitate has been used as a reference standard
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for the generation of calibration curve generation for the quantification of lipids from Azospirillum brasilense
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for the quantification of silk worm embryos and extraembryonic yolk lipids using thin layer chromatography
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for the quantification of triacylglycerol in Neochloris minuta microalgal cells
| | Definition | ChEBI: Tripalmitin is a triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by palmitic (hexadecanoic) acid. It is functionally related to a hexadecanoic acid. | | General Description | SRM 1595_cert SRM 1595 _SDS | | Biochem/physiol Actions | Glyceryl tripalmitate is a carrier molecule for effective drug delivery and is used solid lipid nanoparticle formulations. | | Purification Methods | Crystallise it from acetone, diethyl ether or EtOH. It exists in an -form (m 56.0o), a ’-form (m 63.5o) and a -form (m 65.5o). [Beilstein 2 H 373, 2 I 167, 2 II 340, 2 III 971.] | | References | [1] MIROSLAV LíSA Michal H. Triacylglycerols profiling in plant oils important in food industry, dietetics and cosmetics using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.[J]. Journal of Chromatography A, 2008, 1198-1199: 115-130. DOI: 10.1016/j.chroma.2008.05.037
[2] J H MOFFITT. Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro.[J]. Diabetologia, 2005: 1819-1829. DOI: 10.1007/s00125-005-1861-9
[3] LAKKIREDDY HARIVARDHAN REDDY. Etoposide-incorporated tripalmitin nanoparticles with different surface charge: formulation, characterization, radiolabeling, and biodistribution studies.[J]. AAPS Journal, 2004, 6 3: e23. DOI: 10.1208/aapsj060323 |
| | Tripalmitin Preparation Products And Raw materials |
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