15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER

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15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Basic information
Product Name:15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER
Synonyms:15(R)-15-methyl Prostaglandin F2α methyl ester;QQCOAAFKJZXJFP-IFMFXUMGSA-N;15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER;9ALPHA,11ALPHA,15R-TRIHYDROXY-15-METHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID, METHYL ESTER;Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, methyl ester, (5Z,9α,11α,13E,15R)-
CAS:35700-22-2
MF:C22H38O5
MW:382.53
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Mol File:35700-22-2.mol
15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Structure
15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Chemical Properties
solubility DMF: >50 mg/ml (from PGE2 methyl es; DMSO: >50 mg/ml (from PGE2 methyl es; Ethanol: >50 mg/ml (from PGE2 methyl es; PBS pH 7.2: 5 mg/ml (from PGE2 methyl este
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MSDS Information
15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Usage And Synthesis
Description15(R)-15-methyl Prostaglandin F2α methyl ester (15(R)-15-methyl PGF2α methyl ester) is a lipid soluble prodrug form of 15(R)-15-methyl PGF2α with increased membrane permeability. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2α methyl ester and hydrolysis of the ester converts it into the active 15(S)-15-methyl PGF2α .1,2
Uses15(R)-15-Methyl prostaglandin F2α methyl ester (15(R)-Methyl carboprost) (compound 15R) is a 15-methyl substituted prostaglandin analog, a member of the prostaglandin family, with potential biological activities in a variety of biological systems, but its specific activity mechanism and application details are not described in detail from the existing information.
References1. Plaisted, S.M., DeZwaan, J., and Snider, B.G. High-performance liquid chromatographic determination of acid-catalyzed degradation products of methyl carboprost in a polymeric controlled-release device J. Chromatogr. 314,369-377(1984).
2. Hamberg, M., Zhang, L.Y., and Bergstrm, S. On the pH-dependent degradation of 15(S)-15 methyl-prostaglandin F2α (Carboprost) Eur. J. Pharm. Sci. 3(1),27-38(1995).
15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER Preparation Products And Raw materials
Tag:15(R)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER(35700-22-2) Related Product Information
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