| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
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| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:199331-40-3
CAS:199331-40-3
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Etiprednol dicloacetate
CAS:199331-40-3
Purity:99% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Etiprednol dicloacetate
CAS:199331-40-3
Purity:99.22% Package:1mg/RMB 780;5mg/RMB 1850;10mg/RMB 2730
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etiprednol dicloacetate manufacturers
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| | etiprednol dicloacetate Basic information |
| Product Name: | etiprednol dicloacetate | | Synonyms: | etiprednol dicloacetate;Androsta-1,4-diene-17-carboxylic acid, 17-[(2,2-dichloroacetyl)oxy]-11-hydroxy-3-oxo-, ethyl ester, (11β,17α)-;BNP 166;BNP166;BNP-166;BNP 166|||BNP166|||BNP-166 | | CAS: | 199331-40-3 | | MF: | C24H30Cl2O6 | | MW: | 485.4 | | EINECS: | | | Product Categories: | | | Mol File: | 199331-40-3.mol |  |
| | etiprednol dicloacetate Chemical Properties |
| | etiprednol dicloacetate Usage And Synthesis |
| Uses | Anti-inflammatory corticosteroid. | | Definition | ChEBI: Etiprednol dicloacetate is a steroid ester. | | in vivo | Etiprednol dicloacetate (0-100 μg/kg, intranasal inhalation) attenuates peribronchial eosinophilia in the lung of the allergen sensitized and challenged rats[1].
Etiprednol dicloacetate (0.1 μg/kg, intranasal inhalation) inhibits eosinophil accumulation in rats (antigen-induced airway eosinophil infiltration)[3].
Etiprednol dicloacetate (0-20 mg/kg, p.o., 28 days) is well tolerated in rats and dogs[2].
| Animal Model: | Allergen sensitized and challenged Brown Norway rats[1] | | Dosage: | 0.1, 1, 10, and 100 μg/kg | | Administration: | Intranasal inhalation | | Result: | Decreased the number of eosinophils at the perivascular area of the lung tissue.
Decreased the number of mucus secreting cells and antigen-induced formation of perivascular edema.
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| | etiprednol dicloacetate Preparation Products And Raw materials |
| Raw materials | (8S,9S,10R,11S,13S,14S,17R)-17-(2,2-dichloroacetoxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid-->Diethyl sulfate |
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