- Pranoprofen
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- $68.00 / 500mg
-
2026-04-13
- CAS:52549-17-4
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
- Pranoprofen
-
- $68.00 / 500mg
-
2026-04-13
- CAS:52549-17-4
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
- Pranoprofen
-
- $10.00 / 1kg
-
2026-03-20
- CAS:52549-17-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100 mt
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| | Pranoprofen Basic information |
| | Pranoprofen Chemical Properties |
| Melting point | 182-183° | | Boiling point | 398.5°C (rough estimate) | | density | 1.1654 (rough estimate) | | refractive index | 1.5500 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | powder | | pka | 4.27±0.10(Predicted) | | color | white to beige | | InChI | InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18) | | InChIKey | TVQZAMVBTVNYLA-UHFFFAOYSA-N | | SMILES | C(C1C=CC2OC3=NC=CC=C3CC=2C=1)(C)C(=O)O | | CAS DataBase Reference | 52549-17-4(CAS DataBase Reference) |
| RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | WGK 1 | | RTECS | DJ3100950 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral | | Toxicity | LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga) |
| | Pranoprofen Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Originator | Niflan, Yoshitomi ,Japan ,1981 | | Uses | Pranoprofen is an anti-inflammatory used in ophthalmology. | | Definition | ChEBI: Pranoprofen is a pyridochromene. | | Manufacturing Process | A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C. | | Therapeutic Function | Analgesic, Antiinflammatory | | General Description | Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug. | | Biochem/physiol Actions | Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery. |
| | Pranoprofen Preparation Products And Raw materials |
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