- Triazophos
-
-
2026-07-14
- CAS:24017-47-8
- Min. Order: 1kg
- Purity: 99
- Supply Ability: 20tons
- Triazophos
-
- $10.00
-
2026-03-20
- CAS:24017-47-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Triazophos
-
- $1.00
-
2022-12-29
- CAS:24017-47-8
- Min. Order: 10g
- Purity: 99.5%
- Supply Ability: 1000kg
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| | Triazophos Chemical Properties |
| Melting point | 0-5°C | | Boiling point | 260°C | | density | 1.247 | | vapor pressure | 3.9×10-4 Pa (30 °C) | | Fp | 25 °C | | storage temp. | APPROX 4°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | -0.15±0.50(Predicted) | | form | liquid | | color | Light yellow to brown | | Water Solubility | 30-40 mg/L at 20 ºC | | BRN | 682554 | | Henry's Law Constant | 3.2×102 mol/(m3Pa) at 25℃, HSDB (2015) | | Stability: | Hygroscopic | | Major Application | agriculture
environmental | | InChI | 1S/C12H16N3O3PS/c1-3-16-19(20,17-4-2)18-12-13-10-15(14-12)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3 | | InChIKey | AMFGTOFWMRQMEM-UHFFFAOYSA-N | | SMILES | CCOP(=S)(OCC)Oc1ncn(n1)-c2ccccc2 | | NIST Chemistry Reference | Triazophos(24017-47-8) | | EPA Substance Registry System | Triazophos (24017-47-8) |
| Hazard Codes | T;N,N,T | | Risk Statements | 21-23/25-50/53-38-10 | | Safety Statements | 1/2-36/37-45-60-61 | | RIDADR | 3018 | | WGK Germany | 3 | | RTECS | TF5635000 | | HazardClass | 6.1(a) | | PackingGroup | II | | HS Code | 29339900 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 1 Inhalation
Acute Tox. 3 Oral
Acute Tox. 4 Dermal
Aquatic Acute 1
Aquatic Chronic 1 | | Hazardous Substances Data | 24017-47-8(Hazardous Substances Data) | | Toxicity | LD50 in rats (mg/kg): 82 orally, 1100 dermally (Thier); LD50 in rats (mg/kg): 107 i.p.; in rabbits (mg/kg): 280 dermally (Hay) |
| | Triazophos Usage And Synthesis |
| Description | Triazophos is a Yellowish-brown-oil chemical pesticide used as an insecticide, nematicide and acaricide. The chemical is an organophosphorus compound and ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure. The chemical may be absorbed through the skin. More detailed information about the symptoms, causes, and treatments of Chemical poisoning--Triazophos is available below. It is stable to sunlight and its molecular weight313.312 g/mol. For solublity, It solubles in organic solvents and in acetone, dichloromethane, methanol, isopropanol, ethyl acetate and plyethyleneglycols >500; n-hexane 11.1 (all in g/L at 20 degree). | | Methods of Manufacturing | Triazophos is produced by reaction of 1-phenyl-3-hydroxy-1H-1,2,4-triazole, suspended in acetone, with diethoxythiophosphoryl chloride in the presence of triethylamine.
Physical and chemical properties
The pure product is a pale yellow-brown oily liquid; melting point: 0-5 °C; vapor pressure: 0.39 Mpa; relative density: 1.24; it decomposes at 185 °C before reaching the boiling point and can be degraded by acids and alkalis. | | Uses | Triazophos is a broad-spectrum insecticide and miticide and has a certain degree of nematicidal effects. It has excellent preventive effects on many pests of the major crops including grain, cotton and vegetables, such as stem borers, rice planthoppers, spider mites, cotton bollworms, nematodes, and it is especially effective on the lepidoptera. | | Storage and transportation | It should be protected from the sun, rain and heat sources and kept away from food, seeds and feeds. | | References | 1.http://www.sld.chemchina.com/slden/cpyfw/ppysb/jscg/webinfo/2012/06/1342611935442261.htm
2.https://pubchem.ncbi.nlm.nih.gov/compound/Triazophos
3.https://fr.wikipedia.org/wiki/Triazophos | | Chemical Properties | The industrial product is a yellow liquid with a solubility of 30-40 mg/kg in water. It is easily soluble in acetone, ethyl acetate, and toluene. | | Uses | Triazophos is used to control chewing and sucking insects and
mites in a wide range of crops. It is also used to control some nematodes
in ornamentals and strawberries. | | Uses | An organophosphorus insecticide. | | Uses | Pesticide. | | Definition | ChEBI: Triazophos is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide, an agrochemical and a nematicide. It is functionally related to a 1-phenyl-1H-1,2,4-triazol-3-ol. | | General Description | Yellowish oil. Used to control insects, mites, and nematodes. Not registered as a pesticide in the U.S. | | Reactivity Profile | Organophosphates, such as Triazophos, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | | Health Hazard | This is an organophosphate pesticide. Triazophos is a cholinesterase inhibitor and acts on the central nervous system. Organic phosphorus insecticides are absorbed by the skin as well as by the respiratory and gastrointestinal tracts. | | Fire Hazard | This is an organophosphate pesticide. Some of these materials may burn but none of them ignite readily. Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Degraded by acids and alkalis. | | Agricultural Uses | Insecticide: Triazophos is a broad-spectrum insecticide and acaricide used to control sucking and chewing pests on a variety of crops, including cotton, rice, corn, beets and fruit
trees. Not currently registered for use in the U.S. Not approved for use in EU countries
. There are more than 30
global suppliers
. | | Trade name | HILAZPOPHOS®; HOE 2960 OJ®; HOE
002960®; HOSTATHION®; SUTATHION® | | Mechanism of action | Non-systemic, broad-spectrum with contact and stomach action. Acetylcholinesterase (AchE) inhibitor. | | Synthesis | I. Phenylhydrazine hydrochloride and urea were mixed and heated to 150-160 with stirring, the reaction produced ammonia to get a yellow melt. Cooling, washing, filtration, recrystallization with alcohol to get 1-phenylaminourea (melting point 172 ). 1-phenylaminourea, triethyl orthoformate and toluene were heated with stirring, and the ethanol generated by the reaction was evaporated until no ethanol was evaporated. After the reaction, cooling, filtration, washing, to obtain 1-phenyl-3-hydroxy-1,2,4-triazole (melting point 269-273 ). 1-phenyl-3-hydroxy-1,2,4-triazole was suspended in acetone, O,O-diethylthiophosphoryl chloride was added, and then triethylamine was added dropwise. After dropwise addition, the reaction was stirred at 50 C for 6 h. The reaction was cooled, filtered and the triethylamine hydrochloride was filtered out. The filtrate recovered acetone to get triazophos brown oil.
Second, 33.5g96% of 1-phenyl-3-hydroxy-1,2,4-triazole suspended in 250mL xylene, add the appropriate amount of composite catalyst (TEBAT + DMAP) and potassium carbonate, stirring for 0.5h, and then dropwise addition of 30g of O,O - diethylthiophosphoryl chloride, the reaction temperature of 80 ~ C, the reaction time of 4h, cooling, filtration, filtrate washed with water, drying. The yield reached 86%. Literature [5] describes the use of a BG catalyst, the yield reached 91% to 96%. | | Metabolic pathway | The main route of biotransformation of triazophos is degradation to 1-
pheny1-3-hydroxy-1,2,4-triazole, probably either via hydrolysis of triazophos
oxon or through oxidative cleavage of triazophos itself. The triazole
ring of this metabolite is opened to give 1-phenylsemicarbazide and semicarbazide,
both of which are conjugated in the rat and also degraded to
urea as the main urinary metabolite. | | Degradation | Triazophos is stable to light but is hydrolysed by acids and alkalis (PM). | | Pesticide Type | Insecticide; Acaricide; Nematicide |
| | Triazophos Preparation Products And Raw materials |
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