NEUROPEPTIDE W-30 (RAT)

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NEUROPEPTIDE W-30 (RAT) Suppliers list
Company Name: GL Biochem (Shanghai) Ltd  
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Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
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NEUROPEPTIDE W-30 (RAT) Basic information
Product Name:NEUROPEPTIDE W-30 (RAT)
Synonyms:Neuropeptide W-30 (rat) Preproprotein L8 (42-71) (rat), rL8C, rPPL8 (42-71), NPW-30 (rat);Preproprotein L8 (42-71) (rat), rL8C, rPPL8 (42-71), NPW-30 (rat);H-TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS-THR-VAL-GLY-ARG-ALA-SER-GLY-LEU-LEU-MET-GLY-LEU-ARG-ARG-SER-PRO-TYR-LEU-TRP-OH;RPPL8 (42-71);RL8C;NPW30 (RAT);NEUROPEPTIDE W-30 (RAT);PREPROPROTEIN L8 (42-71) (RAT)
CAS:383415-90-5
MF:C165H249N49O38S
MW:3559.12
EINECS:
Product Categories:
Mol File:383415-90-5.mol
NEUROPEPTIDE W-30 (RAT) Structure
NEUROPEPTIDE W-30 (RAT) Chemical Properties
density 1.47±0.1 g/cm3(Predicted)
storage temp. −20°C
form solid
SequenceTrp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ser-Gly-Leu-Leu-Met-Gly-Leu-Arg-Arg-Ser-Pro-Tyr-Leu-Trp
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
NEUROPEPTIDE W-30 (RAT) Usage And Synthesis
UsesNeuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses[1][2][3].
References[1] Makoto Kawasaki, et al. Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats. J Endocrinol. 2006 Aug;190(2):213-23. DOI:10.1677/joe.1.06636
[2] Nan-Shou Yu, et al. Effects of intracerebroventricular administration of neuropeptide W30 on neurons in the hypothalamic paraventricular nucleus in the conscious rat. Neurosci Lett. 2007 Mar 26;415(2):140-5. DOI:10.1016/j.neulet.2007.01.048
[3] Yukio Shimomura, et al. Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8. J Biol Chem. 2002 Sep 27;277(39):35826-32. DOI:10.1074/jbc.M205337200
NEUROPEPTIDE W-30 (RAT) Preparation Products And Raw materials
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