| Company Name: |
SPIRO PHARMA |
| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
|
| | Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Basic information |
| Product Name: | Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) | | Synonyms: | (2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-methylenetetrahydrofuran-3-yl benzoate;N4,3’,5’-Tribenzoyl,2’-deoxy-2’-methylene Cytidine;Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI);Cytidine, N-benzoyl-2'-deoxy-2'-methylene-, 3',5'-dibenzoate;C31H25N3O7;Sofosbuvir Methylene Impurity;Sofosbuvir Impurity 110;-methyleneCytidine | | CAS: | 863329-63-9 | | MF: | C31H25N3O7 | | MW: | 551.55 | | EINECS: | | | Product Categories: | | | Mol File: | 863329-63-9.mol |  |
| | Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Chemical Properties |
| Melting point | 173.4-174.4 °C(Solv: ethanol (64-17-5)) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | pka | 7.61±0.20(Predicted) | | Appearance | Light yellow to yellow Solid |
| | Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Usage And Synthesis |
| Uses | N4,3'',5''-Tribenzoyl,2''-deoxy-2''-methylene Cytidine is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| | Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Preparation Products And Raw materials |
|