| Company Name: |
ShangHai Biochempartner Co.,Ltd
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| Tel: |
177-54423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:QO-40
CAS:1259536-70-3
Purity:98% HPLC LCMS Package:500mg;1g;10g
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QO-40 manufacturers
- QO-40
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- $50.00 / 25mg
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2026-01-05
- CAS:1259536-70-3
- Min. Order:
- Purity: 99.57%
- Supply Ability: 10g
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| Product Name: | QO-40 | | Synonyms: | QO-40;5-(CHLOROMETHYL)-3-(NAPHTHA LEN-1-YL)-2-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-7(4H)-ONE;QO 40,QO40;Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-(chloromethyl)-3-(1-naphthalenyl)-2-(trifluoromethyl)-;QO-40, 10 mM in DMSO;5-(Chloromethyl)-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H,7H-pyrazolo[1,5-a]pyrimidin-7-one | | CAS: | 1259536-70-3 | | MF: | C18H11ClF3N3O | | MW: | 377.75 | | EINECS: | | | Product Categories: | | | Mol File: | 1259536-70-3.mol |  |
| | QO-40 Chemical Properties |
| Melting point | >300 °C | | Boiling point | 500.6±60.0 °C(Predicted) | | density | 1.51±0.1 g/cm3(Predicted) | | form | Solid | | pka | -4.08±0.40(Predicted) | | color | White to off-white |
| | QO-40 Usage And Synthesis |
| Description | QO-40 is an activator of KCNQ2/3 potassium channels. | | Uses | QO-40 is a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative and an activator of the voltage-gated M-type potassium channel KCNQ encoded by the KCNQ2/3 gene (EC50: 1.25 μM)[1][2]. | | References | [1] Jia C, et al. Activation of KCNQ2/3 potassium channels by novel pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives. Pharmacology. 2011;87(5-6):297-310. DOI:10.1159/000327384 |
| | QO-40 Preparation Products And Raw materials |
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