Defensin HNP-1 (human) manufacturers
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| | Defensin HNP-1 (human) Basic information |
| Product Name: | Defensin HNP-1 (human) | | Synonyms: | Human Defensin NP-1;L-Cysteine, L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanylglycyl-L-α-glutamyl-L-arginyl-L-arginyl-L-tyrosylglycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalan... | | CAS: | 148093-65-6 | | MF: | C150H222N44O38S6 | | MW: | 3442.02968 | | EINECS: | | | Product Categories: | | | Mol File: | 148093-65-6.mol |  |
| | Defensin HNP-1 (human) Chemical Properties |
| density | 1.53±0.1 g/cm3(Predicted) | | Sequence | H-Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (Disulfide bonds between Cys2 and Cys3/Cys and Cys1/Cys and Cys2) |
| | Defensin HNP-1 (human) Usage And Synthesis |
| Uses | Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development. Defensin HNP-1 human exhibits broad antimicrobial and anti-leishmanial activities[1][2]. | | IC 50 | Leishmania | | References | [1] Dabirian S, et, al. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate. PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2491. DOI:10.1371/journal.pntd.0002491
[2] Higazi M, et, al. Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis. PLoS One. 2020 Apr 17;15(4):e0231582. DOI:10.1371/journal.pone.0231582 |
| | Defensin HNP-1 (human) Preparation Products And Raw materials |
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