ALPHA-DEFENSIN-3 (HUMAN) manufacturers
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| | ALPHA-DEFENSIN-3 (HUMAN) Basic information |
| Product Name: | ALPHA-DEFENSIN-3 (HUMAN) | | Synonyms: | DEFENSIN HNP-3 (HUMAN);H-ASP-CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS-OH, (DISULFIDE BONDS BETWEEN CYS2 AND CYS30/CYS4 AND CYS19/ CYS9 AND CYS29);Defensin HNP-1 (huMan)
HuMan Neutrophil Peptide-1, HNP-1;Defensin HNP-3 (huMan)
HuMan Neutrophil Peptide-3, HNP-3;H-Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH;HuMan Neutrophil Peptide-3, HNP-3;H-Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH;HuMan Neutrophil Peptide-1, HNP-1 | | CAS: | 136661-76-2 | | MF: | C151H222N44O40S6 | | MW: | 3486.04 | | EINECS: | | | Product Categories: | | | Mol File: | 136661-76-2.mol |  |
| | ALPHA-DEFENSIN-3 (HUMAN) Chemical Properties |
| density | 1.54±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | Sequence | H-Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bonds between Cys2 and Cys3/Cys and Cys1/Cys and Cys2) |
| | ALPHA-DEFENSIN-3 (HUMAN) Usage And Synthesis |
| Uses | Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2]. | | References | [1] Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9. DOI:10.1172/JCI118588
[2] Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435. |
| | ALPHA-DEFENSIN-3 (HUMAN) Preparation Products And Raw materials |
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