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| | Fluorescein-PEG6-bis-NHS ester Basic information |
| Product Name: | Fluorescein-PEG6-bis-NHS ester | | Synonyms: | Fluorescein-PEG6-bis-NHS ester;4,7,10,13,16,19-Hexaoxa-22-azatricosanoic acid, 23-[[4-(3,6-dihydroxy-9H-xanthen-9-yl)-3-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]amino]-23-thioxo-, 2,5-dioxo-1-pyrrolidinyl ester | | CAS: | 2055105-59-2 | | MF: | C44H50N4O17S | | MW: | 938.95 | | EINECS: | | | Product Categories: | | | Mol File: | 2055105-59-2.mol |  |
| | Fluorescein-PEG6-bis-NHS ester Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| | Fluorescein-PEG6-bis-NHS ester Usage And Synthesis |
| Description | Fluorescein-PEG6-bis-NHS ester is a fluorescein labeled PEG linker containing two NHS groups, which enables labeling for antibodies and other purified proteins at primary amines (lysine side chains). The hydrophilic PEG spacer arm increases solubility in aqueous media. | | Uses | Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Fluorescein-PEG6-bis-NHS ester Preparation Products And Raw materials |
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