Fluorescein-PEG6-bis-NHS ester

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Fluorescein-PEG6-bis-NHS ester
CAS:2055105-59-2
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:Fluorescein-PEG6-bis-NHS ester
CAS:2055105-59-2
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
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Products Intro: Product Name:Fluorescein-PEG6-bis-NHS ester
CAS:2055105-59-2
Purity:95% Package:$601.9/1mg;$841.9/2mg;$1621.9/5mg;Bulk package Remarks:95%
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Products Intro: Product Name:Fluorescein-PEG6-bis-NHS ester
CAS:2055105-59-2
Purity:99% HPLC Package:5KG;1KG
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Products Intro: Product Name:Fluorescein-PEG6-bis-NHS ester
CAS:2055105-59-2
Purity:98% Package:1g;5g;10g
Fluorescein-PEG6-bis-NHS ester Basic information
Product Name:Fluorescein-PEG6-bis-NHS ester
Synonyms:Fluorescein-PEG6-bis-NHS ester;4,7,10,13,16,19-Hexaoxa-22-azatricosanoic acid, 23-[[4-(3,6-dihydroxy-9H-xanthen-9-yl)-3-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]amino]-23-thioxo-, 2,5-dioxo-1-pyrrolidinyl ester
CAS:2055105-59-2
MF:C44H50N4O17S
MW:938.95
EINECS:
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Mol File:2055105-59-2.mol
Fluorescein-PEG6-bis-NHS ester Structure
Fluorescein-PEG6-bis-NHS ester Chemical Properties
solubility Soluble in Water, DMSO, DMF, DCM
Safety Information
MSDS Information
Fluorescein-PEG6-bis-NHS ester Usage And Synthesis
DescriptionFluorescein-PEG6-bis-NHS ester is a fluorescein labeled PEG linker containing two NHS groups, which enables labeling for antibodies and other purified proteins at primary amines (lysine side chains). The hydrophilic PEG spacer arm increases solubility in aqueous media.
UsesFluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fluorescein-PEG6-bis-NHS ester Preparation Products And Raw materials
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