3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:Roxindole CAS:112192-04-8 Purity:99.18% Package:1mg;293USD\|5mg;722USD\|10mg;987USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Career Henan Chemica Co
Tel:	+86-0371-86658258 +8613203830695
Email:	laboratory@coreychem.com
Products Intro:	Product Name: 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE CAS:112192-04-8 Purity:Min98% HPLC/GC Package:1KG;8USD

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:Roxindole hydrochloride CAS:112192-04-8 Purity:>98% Package:$228.9/10mg;$912.9/50mg;Bulk package Remarks:>98%

Company Name:	DAYANG CHEM (HANGZHOU) CO.,LTD
Tel:	+86-88938639 +86-17705817739
Email:	info@dycnchem.com
Products Intro:	Product Name:Roxindole hydrochloride CAS:112192-04-8 Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Hot selling

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	821-50328103-801 18930552037
Email:	3bsc@sina.com
Products Intro:	Product Name:Roxindole hydrochloride;3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-olhydrochloride CAS:112192-04-8 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE manufacturers

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Basic information

Product Name:	3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
Synonyms:	3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE;ROXINDOLE HYDROCHLORIDE;Roxindole;RoxindoleHCl;3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol;3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol;Roxindole [inn];1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-
CAS:	112192-04-8
MF:	C23H26N2O
MW:	346.47
EINECS:
Product Categories:	Dopamine receptor
Mol File:	112192-04-8.mol

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Chemical Properties

Melting point	>165°C (dec.)
Boiling point	575.7±50.0 °C(Predicted)
density	1.173±0.06 g/cm3(Predicted)
storage temp.	Desiccate at -20°C
solubility	DMSO (Slightly), Water (Slightly)
pka	10.15±0.40(Predicted)
form	Solid
color	Pale Beige to Light Beige
Stability:	Hygroscopic

Safety Information

MSDS Information

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Usage And Synthesis

Uses	Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist.
Definition	ChEBI: Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug.
Biological Activity	Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo .
in vivo	Roxindole inhibits apomorphine-induced climbing in mice and stereotyped behavior in rats with ED₅₀s of 1.4 mg/kg s.c. and 0.65 mg/kg s.c., respectively, and inhibits conditioned avoidance response in rats (ED₅₀=1.5 mg/kg s.c.)^[1]. Roxindole (EMD 49980) (1, 3, 10 mg/kg; s.c) inhibits both effects of 8-OH-DPAT (flat body and forepaw treading) in normal rats (male Wistar 200-350g)^[3].

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Preparation Products And Raw materials

Tag:3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE(112192-04-8) Related Product Information

ROXINDOLE MESYLATE 3-(4-(4-PHENYL-1,2,3,6-TETRAHYDRO-1-PYRIDYL)BUTYL)INDOLE, HCL 1,2,3,6-Tetrahydro-4-phenyl-pyridine 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

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