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| | Trimetazidine N-oxide Basic information |
| Product Name: | Trimetazidine N-oxide | | Synonyms: | Trimetazidine N-oxide;Trimetazidine N-Oxide HCl;Trimetazidine N-Oxide DiHCl/1-(2,3,4-Trimethoxybenzyl)piperazine 1-oxide dihydrochloride;Piperazine, 1-hydroxy-4-[(2,3,4-trimethoxyphenyl)methyl]- | | CAS: | 1644530-89-1 | | MF: | C14H22N2O4 | | MW: | 282.34 | | EINECS: | | | Product Categories: | | | Mol File: | 1644530-89-1.mol |  |
| | Trimetazidine N-oxide Chemical Properties |
| Boiling point | 397.1±42.0 °C(Predicted) | | density | 1.196±0.06 g/cm3(Predicted) | | pka | 13.23±0.20(Predicted) |
| | Trimetazidine N-oxide Usage And Synthesis |
| Uses | Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. | | References | [1] Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205. DOI:10.1002/dta.1680 |
| | Trimetazidine N-oxide Preparation Products And Raw materials |
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