methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride manufacturers
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| | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Basic information |
| Product Name: | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride | | Synonyms: | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride;(R)-METHYL 2-AMINO-3-(7-METHYL-1H-INDAZOL-5-YL)PROPANOATE 2HCL;(R)-Methyl 2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride;Methyl (R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride;1H-Indazole-5-propanoic acid, α-amino-7-methyl-, methyl ester, hydrochloride (1:2), (αR)-;methyl (R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate hydrochloride;Zavegepant Impurity 108 Dihydrochloride | | CAS: | 1414976-14-9 | | MF: | C12H16ClN3O2 | | MW: | 269.73 | | EINECS: | | | Product Categories: | | | Mol File: | 1414976-14-9.mol |  |
| | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Chemical Properties |
| InChI | InChI=1/C12H15N3O2.ClH/c1-7-3-8(5-10(13)12(16)17-2)4-9-6-14-15-11(7)9;/h3-4,6,10H,5,13H2,1-2H3,(H,14,15);1H/t10-;/s3 | | InChIKey | FNDDCJUEQKEEQV-MEQOOBBNNA-N | | SMILES | CC1C=C(C[C@@H](N)C(=O)OC)C=C2C=NNC=12.Cl |&1:5,r| |
| | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Usage And Synthesis |
| Uses | Methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride is a crucial intermediate of Zavegepant. It contains a single chiral centre, whose formation is catalyzed by a transaminase. | | Application | Methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride is mainly used as an organic synthesis intermediate for the preparation of CGRP receptor antagonist migraine drugs (such as zavigepan). |
| | methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Preparation Products And Raw materials |
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