CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)

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CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) manufacturers

  • CR 665
  • CR 665 pictures
  • $1980.00
  • 2026-07-15
  • CAS:228546-92-7
  • Purity:
  • Supply Ability: 10g
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Basic information
Product Name:CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)
Synonyms:CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl);D-Argininamide, D-phenylalanyl-D-phenylalanyl-D-norleucyl-N-(4-pyridinylmethyl)-;FE 200665|||JNJ 38488502
CAS:228546-92-7
MF:C36H49N9O4
MW:671.83
EINECS:
Product Categories:
Mol File:228546-92-7.mol
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Structure
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Chemical Properties
density 1.26±0.1 g/cm3(Predicted)
pka13.36±0.46(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Usage And Synthesis
UsesCR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain[1][2].
References[1] Anne E Olesen, et al. A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone. Clin Pharmacokinet DOI:10.1007/s40262-012-0023-8
[2] Francis M Hughes Jr, et al. Development of a Peptide-derived orally-active kappa-opioid receptor agonist targeting peripheral pain. Open Med Chem J. 2013 Nov 4;7:16-22. DOI:10.2174/1874104501307010016
CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl) Preparation Products And Raw materials
Tag:CR665 (H-D-Phe-D-Phe-D-Nle-D-Arg-NH-4-Picolyl)(228546-92-7) Related Product Information
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