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AMG2850 manufacturers
- AMG2850
-
- $68.00
-
2026-07-17
- CAS:1470018-52-0
- Purity: 99.84%
- Supply Ability: 10g
- AMG2850
-
- $68.00
-
2026-07-17
- CAS:1470018-52-0
- Purity: 99.84%
- Supply Ability: 10g
- AMG2850
-
- $68.00
-
2025-05-12
- CAS:1470018-52-0
- Purity: 99.05%
- Supply Ability: 10g
|
| | AMG2850 Basic information |
| Product Name: | AMG2850 | | Synonyms: | ((R)-8-(4-(TRIFLUOROMETHYL)PHENYL)-N-((S)-1,1,1-TRIFLUOROPROPAN-2-YL)-5,6-DIHYDRO-1,7-NAPHTHYRIDINE-7(8H)-CARBOXAMIDE);AMG2850;AMG 2850,Inhibitor,AMG2850,inhibit,AMG-2850,Transient receptor potential channels,TRP Channel;1,7-Naphthyridine-7(6H)-carboxamide, 5,8-dihydro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-8-[4-(trifluoromethyl)phenyl]-, (8R)-;AMG2850, 10 mM in DMSO | | CAS: | 1470018-52-0 | | MF: | C19H17F6N3O | | MW: | 417.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1470018-52-0.mol |  |
| | AMG2850 Chemical Properties |
| Boiling point | 452.7±45.0 °C(Predicted) | | density | 1.354±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 11.53±0.40(Predicted) | | color | White to off-white |
| | AMG2850 Usage And Synthesis |
| Description | AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1].
TRPM8[1]. | | Uses | AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1]. | | References | [1]. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76. |
| | AMG2850 Preparation Products And Raw materials |
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