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CRF (6-33) (human, rat) manufacturers
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| | CRF (6-33) (human, rat) Basic information |
| Product Name: | CRF (6-33) (human, rat) | | Synonyms: | ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER;CORTICOTROPIN RELEASING FACTOR FRAGMENT 6-33, HUMA;CORTICOTROPIN-RELEASING FACTOR (6-33) (HUMAN, RAT);CORTICOTROPIN RELEASING FACTOR FRAGMENT 6-33, HUMAN, RAT;CRF (6-33);H-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-OH;CRF (6-33) (human, rat) H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH;6-33-Corticotropin-releasing factor (human) (9CI) | | CAS: | 120066-38-8 | | MF: | C141H231N41O43S | | MW: | 3220.66 | | EINECS: | | | Product Categories: | CRF;CRFPeptides for Cell Biology;Neuropeptides;Releasing Factors;CRF receptor and related | | Mol File: | 120066-38-8.mol |  |
| | CRF (6-33) (human, rat) Chemical Properties |
| density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | Powder | | color | White to off-white | | Water Solubility | Soluble to 1 mg/ml in water | | InChIKey | XHHPINGDTRCKNN-QZXFXOMNSA-N |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | CRF (6-33) (human, rat) Usage And Synthesis |
| Uses | CRF(6-33)(human) is a CRF binding protein (CRF-BP) ligand inhibitor. CRF(6-33)(human) competitively binds the CRF-BP but not the post-synaptic CRF receptors. CRF(6-33)(human) has anti-obesity effect[1][2]. | | Biochem/physiol Actions | CRF fragment that binds with high affinity to the CRF binding protein (CRF-BP) but has low affinity for the CRF receptor. Displaces CRF from CRF-BP. | | References | [1] S C Heinrichs, et al. Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav Brain Res. 2001 Jul;122(1):43-50. DOI:10.1016/s0166-4328(01)00174-7
[2] S C Heinrichs, et al. Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol Behav. 2001 Sep 1-15;74(1-2):5-13. DOI:10.1016/s0031-9384(01)00421-8 |
| | CRF (6-33) (human, rat) Preparation Products And Raw materials |
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