4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE manufacturers
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| | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE Basic information |
| Product Name: | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE | | Synonyms: | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE;Benzonitrile, 4-[7-hydroxy-2-(1-methylethyl)-4-oxo-3(4H)-quinazolinyl]-;TRP Channel,inhibit,Vanilloid receptor antagonist1,Vanilloid receptor antagonist 1,Vanilloid receptor antagonist-1,Inhibitor,Transient receptor potential channels;Vanilloid receptor antagonist 1, 10 mM in DMSO;4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile;libvatrep;Vanilloid receptor antagonist 1 | | CAS: | 871814-52-7 | | MF: | C18H15N3O2 | | MW: | 305.33 | | EINECS: | | | Product Categories: | | | Mol File: | 871814-52-7.mol |  |
| | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE Chemical Properties |
| Boiling point | 551.5±60.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (327.51 mM; Need ultrasonic)|Methanol : 17.86 mg/mL (58.49 mM; ultrasonic and warming and heat to 60°C) | | form | Solid | | pka | 6+-.0.20(Predicted) | | color | White to light yellow |
| | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE Usage And Synthesis |
| Uses | Vanilloid receptor antagonist 1 is a potent vanilloid receptor TRPV1 antagonist extracted from patent US8349852B2, compound B8[1]. | | IC 50 | TRPV1 | | References | [1] Weichun Chen, et al. Quinazolinone derivatives useful as vanilloid antagonists. US8349852B2. |
| | 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE Preparation Products And Raw materials |
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