N-(6-chloropyridin-3-yl)-4-fluorobenzamide

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N-(6-chloropyridin-3-yl)-4-fluorobenzamide manufacturers

  • ZTZ240
  • ZTZ240 pictures
  • 2026-07-29
  • CAS:325457-98-5
  • Purity: 99.89%
  • Supply Ability: 10g
N-(6-chloropyridin-3-yl)-4-fluorobenzamide Basic information
Product Name:N-(6-chloropyridin-3-yl)-4-fluorobenzamide
Synonyms:N-(6-chloropyridin-3-yl)-4-fluorobenzamide;ZTZ 240;ZTZ-240;Benzamide, N-(6-chloro-3-pyridinyl)-4-fluoro-;ZTZ240
CAS:325457-98-5
MF:C12H8ClFN2O
MW:250.66
EINECS:
Product Categories:
Mol File:325457-98-5.mol
N-(6-chloropyridin-3-yl)-4-fluorobenzamide Structure
N-(6-chloropyridin-3-yl)-4-fluorobenzamide Chemical Properties
Boiling point 307.2±37.0 °C(Predicted)
density 1.410±0.06 g/cm3(Predicted)
pka11.59±0.70(Predicted)
Safety Information
MSDS Information
N-(6-chloropyridin-3-yl)-4-fluorobenzamide Usage And Synthesis
DescriptionZTZ240 is a KCNQ2 K+ channel activator which offers a new target to treat hyperexcitability disorders.
Usesztz240 is a chemical modulator of voltage-gated potassium channel Kv7 (KCNQ) (KCNQ2 and 3: EC50=6.1 μM; KCNQ4: EC50=12.2 μM). ztz240 can be used in analgesia and anti-epileptic research[1].
IC 50KV7.2: 6.1 μM (EC50); KV7.3: 6.1 μM (EC50); KV7.4: 12.2 μM (EC50)
References[1] Gao Z, et al. Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions[J]. Journal of Biological Chemistry, 2010, 285(36): 28322-28332. DOI:10.1074/jbc.M110.116392
N-(6-chloropyridin-3-yl)-4-fluorobenzamide Preparation Products And Raw materials
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