| Company Name: |
Ark Pharm, Inc. |
| Tel: |
847-367-3680 |
| Email: |
sales@arkpharminc.com |
| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
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| | Methyl 2-methoxy-5-sulfamoylbenzoate Basic information |
| | Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties |
| Melting point | 175-177 °C (lit.) | | Boiling point | 439.8±55.0 °C(Predicted) | | density | 1.360±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 9.94±0.60(Predicted) | | color | White to Off-White | | InChI | InChI=1S/C9H11NO5S/c1-14-8-4-3-6(16(10,12)13)5-7(8)9(11)15-2/h3-5H,1-2H3,(H2,10,12,13) | | InChIKey | MKDYDRQLKPGNNU-UHFFFAOYSA-N | | SMILES | C(OC)(=O)C1=CC(S(N)(=O)=O)=CC=C1OC | | LogP | 0.36 | | CAS DataBase Reference | 33045-52-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 2922500090 | | Storage Class | 11 - Combustible Solids |
| | Methyl 2-methoxy-5-sulfamoylbenzoate Usage And Synthesis |
| Uses | Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents. | | Preparation | Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.
synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate | | General Description | Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate. |
| | Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials |
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