N-Oleoyl Leucine manufacturers
- N-Oleoyl Leucine
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- $156.00
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2026-05-11
- CAS:136560-76-4
- Purity: 98.25%
- Supply Ability: 10g
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| | N-Oleoyl Leucine Basic information |
| Product Name: | N-Oleoyl Leucine | | Synonyms: | N-Oleoyl Leucine;NOleoyl Leucine,N Oleoyl Leucine;L-Leucine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-;N-[(9Z)-1-oxo-9-octadecen-1-yl]-L-leucine | | CAS: | 136560-76-4 | | MF: | C24H45NO3 | | MW: | 395.62 | | EINECS: | | | Product Categories: | | | Mol File: | 136560-76-4.mol |  |
| | N-Oleoyl Leucine Chemical Properties |
| Boiling point | 560.0±43.0 °C(Predicted) | | density | 0.942±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml; DMSO: 12 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 200 μg/ml | | pka | 3.67±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | N-Oleoyl Leucine Usage And Synthesis |
| Description | N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro.1 N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity. | | Uses | N-Oleoyl leucine is aleucine derivatives. | | Definition | ChEBI: N-oleoyl-L-leucine is an L-leucine derivative resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-leucine. It is a L-leucine derivative and a N-(fatty acyl)-L-alpha-amino acid. It is functionally related to an oleic acid. It is a conjugate acid of a N-oleoyl-L-leucinate. | | References | 1. Long, J.Z., Svensson, K.J., Bateman, L.A., et al. The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria Cell 166(2),1-12(2016). |
| | N-Oleoyl Leucine Preparation Products And Raw materials |
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