1777832-90-2 manufacturers
- TBAP-001
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- $35.00
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2026-08-30
- CAS:1777832-90-2
- Purity: 99.28%
- Supply Ability: 10g
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| | 1777832-90-2 Basic information |
| Product Name: | 1777832-90-2 | | Synonyms: | BAL3833;TBAP-001;Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-N'-[3-(1,1-dimethylethyl)-1-(3-fluorophenyl)-1H-pyrazol-5-yl]-;pancreatic,TBAP-001,lung,Raf kinases,melanoma,Raf,inhibit,TBAP001,TBAP 001,carcinoma,Inhibitor,colorectal;BAL3833(TBAP-001);1-(3-(tert-butyl)-1-(3-fluorophenyl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea;TBAP-001, 10 mM in DMSO | | CAS: | 1777832-90-2 | | MF: | C27H23F2N7O3 | | MW: | 531.51 | | EINECS: | | | Product Categories: | | | Mol File: | 1777832-90-2.mol |  |
| | 1777832-90-2 Chemical Properties |
| density | 1.42±0.1 g/cm3(Predicted) | | pka | 8.41±0.20(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | 1777832-90-2 Usage And Synthesis |
| Uses | TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay[1]. | | References | [1] Caroline Joy, et al. 1 -(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, |
| | 1777832-90-2 Preparation Products And Raw materials |
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