CMP3a

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CMP3a Suppliers list
Company Name: AdooQ Bioscience CHINA  
Tel: 025-58849295
Email: info@adooq.cn
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Tel: 15869524721
Email: 3525679403@qq.com
Company Name: InvivoChem  
Tel: 13549236410
Email: sales@invivochem.cn
Company Name: Beijing Biocreative Technology Co., Ltd.  
Tel: 15522676233
Email: 3007606172@qq.com

CMP3a manufacturers

  • CMP3a
  • CMP3a pictures
  • $3100.00
  • 2026-08-11
  • CAS:2225902-88-3
  • Purity:
  • Supply Ability: 10g
CMP3a Basic information
Product Name:CMP3a
Synonyms:CMP3a;2-Thiophenecarboxamide, 5-[7-[1-[2-(dimethylamino)ethyl]-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-3-[(1S)-1-[2-(trifluoromethyl)phenyl]ethoxy]-;(S)-5-(7-(1-(2-(Dimethylamino)ethyl)-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide;NBI-961 (CMP3a)
CAS:2225902-88-3
MF:C28H27F3N6O2S
MW:568.62
EINECS:
Product Categories:
Mol File:2225902-88-3.mol
CMP3a Structure
CMP3a Chemical Properties
density 1.39±0.1 g/cm3(Predicted)
pka15.23±0.50(Predicted)
Safety Information
MSDS Information
CMP3a Usage And Synthesis
DescriptionCMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
UsesNek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1].
IC 50NEK2: 15 nM (IC50)
References[1] Hong-Yu Li, et al. Small molecule inhibitors of nek2 and uses thereof. WO2018081719A1.
CMP3a Preparation Products And Raw materials
Tag:CMP3a(2225902-88-3) Related Product Information
2,4,6-Heptatrienamide, N-hydroxy-7-phenyl-, (2E,4E,6E)- MBM-17S 3-[5-(aminomethyl)-6-fluoro-1-oxo-2,3-dihydro-1H-isoindol-2-yl]hexahydropyridine-2,6-dione hydrochloride Acetamide, 2-[[(ethylamino)carbonyl](3-pyridinylmethyl)amino]-N-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)- AP4-43 N-(4-Mesitylthiazol-2-yl)benzaMide