COX-2 Monoclonal Antibody (Clone 12C10)

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COX-2 Monoclonal Antibody (Clone 12C10) Suppliers list
Company Name: Shanghai Universal Biotech Co.,Ltd  
Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
COX-2 Monoclonal Antibody (Clone 12C10) Basic information
Product Name:COX-2 Monoclonal Antibody (Clone 12C10)
Synonyms:COX-2 Monoclonal Antibody (Clone 12C10)
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MW:0
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COX-2 Monoclonal Antibody (Clone 12C10) Structure
COX-2 Monoclonal Antibody (Clone 12C10) Chemical Properties
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COX-2 Monoclonal Antibody (Clone 12C10) Usage And Synthesis
DescriptionCyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; ), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 . COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman''s COX-2 Monoclonal Antibody (Clone 12C10) can be used for ELISA, flow cytometry (FC), immunofluorescence (IF), and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, mouse, and ovine samples.
References[1] JIALI FANG. Epigenetic changes mediated by microRNA miR29 activate cyclooxygenase 2 and lambda-1 interferon production during viral infection.[J]. ACS Applied Energy Materials, 2012: 1010-1020. DOI: 10.1128/jvi.06169-11
COX-2 Monoclonal Antibody (Clone 12C10) Preparation Products And Raw materials
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