5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯]
| 中文名称 | 5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯] |
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| 中文同义词 | 2'-氟-5-甲基-2'-脱氧阿糖DU 亚磷酰胺单体;5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯];5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯];化合物 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXY-2'-FLUORO-5-METHYL-B-D-ARABINOURIDINE-3'-CED-PHOSPHORAMIDITE;2'-氟-阿糖-5-甲基-尿苷亚磷酰胺单体;5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-氟-2'-脱氧阿糖-5-甲基-尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯];2'-F-ANA-5-Me-U亚磷酰胺单体;2'-F-ANA-5-Me-U亚磷酰胺 |
| 英文名称 | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite |
| 英文同义词 | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite;1-[2-DEOXY-2-FLUORO-5-O-DMTr-B-D-ARABINOFURANOSYL]- THYMINE-3-O-CE-AMIDITE;5’-O-(4,4’-Dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methyl-b-D-arabinouridine-3’-CED-phosphoramidite;2’-Deoxy-2’-fluoro-5-Me-ara-U-3’-CED-phosphoramidite;2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-;1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite;(2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;2’-F-ANA-5-Me-rU CE Phosphoramidite |
| CAS号 | 208193-48-0 |
| 分子式 | C40H48FN4O8P |
| 分子量 | 762.82 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 208193-48-0.mol |
| 结构式 | ![5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯] 结构式](CAS/20211123/GIF/208193-48-0.gif) |
5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯] 性质
| 溶解度 | DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Sparingly Soluble: 1-10 mg/ml |
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| 酸度系数(pKa) | 9.55±0.10(Predicted) |
5'-O-DMTR-2'-氟-5-甲基-2'-脱氧阿糖尿苷-3'-[2-氰基乙基二异丙基氨基亚磷酸酯] 是一种胸腺嘧啶核苷类似物。该系列的类似物对复制的 DNA 具有插入活性。它们可用于标记细胞，追踪 DNA 合成。