Fmoc-NH-PEG11-CH2CH2COOH

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CAS:2291257-76-4
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Products Intro: Product Name:Fmoc-PEG11-acetic acid
CAS:2291257-76-4
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CAS:2291257-76-4
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CAS:2291257-76-4
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Products Intro: Product Name:Fmoc-NH-PEG11-CH2CH2COOH
CAS:2291257-76-4
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  • Fmoc-NH-PEG12-CH2COOH
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  • $1064.00 / 1g
  • 2025-12-16
  • CAS:2291257-76-4
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  • Purity: 98%
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Fmoc-NH-PEG11-CH2CH2COOH Basic information
Product Name:Fmoc-NH-PEG11-CH2CH2COOH
Synonyms:Fmoc-NH-PEG11-CH2CH2COOH;Fmoc-PEG11-acetic acid;Fmoc-N-Amido-PEG12-CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azadotetracontan-42-oic acid;Fmoc-NH-PEG12-acetic Acid
CAS:2291257-76-4
MF:C41H63NO16
MW:825.95
EINECS:
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Mol File:2291257-76-4.mol
Fmoc-NH-PEG11-CH2CH2COOH Structure
Fmoc-NH-PEG11-CH2CH2COOH Chemical Properties
Boiling point 863.2±65.0 °C(Predicted)
density 1.182±0.06 g/cm3(Predicted)
pka3.39±0.10(Predicted)
form Viscous Liquid
color Colorless to light yellow
Safety Information
MSDS Information
Fmoc-NH-PEG11-CH2CH2COOH Usage And Synthesis
UsesFmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological ActivityFmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50PEGs; Alkyl/ether
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Fmoc-NH-PEG11-CH2CH2COOH Preparation Products And Raw materials
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