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| | NEURODYE RH-237, PURE Basic information |
| Product Name: | NEURODYE RH-237, PURE | | Synonyms: | Neurodye RH-237N-(4-Sulfobutyl)-4-(6-(4-dibutylamino)phenyl)hexatrienyl)pyridinium, inner saltRH-237;NEURODYE RH-237, PURE;4-(6-(4-dibutylaminophenyl)-1,3,5-hexatrienyl)-1-(4'-sulfobutyl)pyridinium;4-(n,n-dibutylanilino)hexatrienyl-40-
pyridinium Butanesulfonate;RH237 Membrane Potential Fluorescent Probes (NIR);N-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)benzamide | | CAS: | 83668-91-1 | | MF: | C29H40N2O3S | | MW: | 496.71 | | EINECS: | | | Product Categories: | Styryl | | Mol File: | 83668-91-1.mol |  |
| | NEURODYE RH-237, PURE Chemical Properties |
| Melting point | >200℃ | | solubility | Soluble in ethanol, methanol, dimethyl
sulfoxide | | form | Solid | | pka | 1.694±0.50(predicted) | | Appearance | dark violet powder | | λmax | 528 nm | | Biological Applications | Measuring membrane potential; detecting Na+/K+-ATPase; examining activity of ion channels |
| | NEURODYE RH-237, PURE Usage And Synthesis |
| Description | RH 237, also called N-(4-sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, is a fast-response potential-sensitive probe. RH 237 is primarily used for imaging membrane potential, synaptic activity, and ion channel activity of neurons. However, the dye is also suitable for imaging the functional activity of mitochondria and heart cells.
Excitation/emission maxima of RH 237 in ethanol are 532/777 nm, respectively. In cell membranes, the spectra of the dye are typically blue-shifted by approximately 20 nm for excitation and 80 nm for emission peaks.
Use 1-5 μM working concentration as a starting point. The exact dye concentration should be defined experimentally. | | Abs/Em Maxima | 532/777 nm |
| | NEURODYE RH-237, PURE Preparation Products And Raw materials |
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