| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
LY-3381916 manufacturers
- LY3381916
-
- $34.00
-
2026-07-27
- CAS:2166616-75-5
- Purity: 99.30%
- Supply Ability: 10g
- LY3381916
-
- $34.00
-
2026-07-27
- CAS:2166616-75-5
- Purity: 99.30%
- Supply Ability: 10g
- LY-3381916
-
-
2026-07-22
- CAS:2166616-75-5
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
|
| | LY-3381916 Basic information |
| Product Name: | LY-3381916 | | Synonyms: | LY-3381916;Benzamide, N-[(1R)-1-[2,3-dihydro-1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-1H-indol-5-yl]ethyl]-4-fluoro-;LY3381916 (IDO1-IN-5);Indoleamine 2,3-Dioxygenase (IDO),IDO1IN5,inhibit,Inhibitor,IDO-1-IN-5,IDO1 IN 5;4-fluoro-N-{(1R)-1-[1-(tetrahydro-2H-pyran-4-ylcarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}benzamide;IDO1-IN-5, 10 mM in DMSO;(R)-4-fluoro-N-(1-(1-(tetrahydro-2H-pyran-4-carbonyl)indolin-5-yl)ethyl)benzamide | | CAS: | 2166616-75-5 | | MF: | C23H25FN2O3 | | MW: | 396.45 | | EINECS: | | | Product Categories: | | | Mol File: | 2166616-75-5.mol |  |
| | LY-3381916 Chemical Properties |
| Boiling point | 665.5±55.0 °C(Predicted) | | density | 1.251±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml | | form | A crystalline solid | | pka | 13.93±0.46(Predicted) | | color | White to off-white |
| | LY-3381916 Usage And Synthesis |
| Uses | LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1]. | | IC 50 | IDO1 | | References | [1] Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13). |
| | LY-3381916 Preparation Products And Raw materials |
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