LolCDE-IN-1
| 中文名称 | LolCDE-IN-1 |
|---|---|
| 中文同义词 | 化合物LOLCDE-IN-1;4-(3-(3-((4-氟苄基)氧基)苯基)-1H-吡唑-4-基)吡啶;化合物LOLCDE-IN-1,10 MM DMSO 溶液 |
| 英文名称 | LolCDE-IN-1 |
| 英文同义词 | LolCDE-IN-1;Pyridine, 4-[3-[3-[(4-fluorophenyl)methoxy]phenyl]-1H-pyrazol-4-yl]-;antibacterial,inhibit,Bacterial,LolCDEIN1,Inhibitor,LolCDE IN 1,LolCDE;4-[3-[3-[(4-fluorophenyl)methoxy]phenyl]-1H-pyrazol-4-yl]pyridine;4-(3-(3-((4-Fluorobenzyl)oxy)phenyl)-1H-pyrazol-4-yl)pyridine;LolCDE-IN-1, 10 mM in DMSO |
| CAS号 | 1639933-78-0 |
| 分子式 | C21H16FN3O |
| 分子量 | 345.37 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1639933-78-0.mol |
| 结构式 |  |
LolCDE-IN-1 性质
| 沸点 | 529.9±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.261±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：41.67 mg/mL（120.65 mM） |
| 形态 | 固体 |
| 酸度系数(pKa) | 10.76±0.50(Predicted) |
| 颜色 | 浅黄至黄色 |
LolCDE-IN-1 是一种 LolCDE 复合物的抑制剂，具有抗菌活性。
Bacterial
LolCDE-IN-1 (compound 2) inhibits the function of the LolCDE complex, which is required for transport of lipoproteins to the outer membrane.
LolCDE-IN-1 inhibits E. coli ATCC 25922 and E. coli ATCC 25922 ΔtolCwith MIC with 8 μg/ml and 0.125 μg/ml.
LolCDE-IN-1 inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-130839 | LolCDE-IN-1 | 1639933-78-0 | 1 mg | 669元 |
| 2025/12/22 | HY-130839 | LolCDE-IN-1 LolCDE-IN-1 | 1639933-78-0 | 10mM * 1mLin DMSO | 1264元 |