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| | C22 Galactosylceramide (d18:1/22:0) Basic information |
| Product Name: | C22 Galactosylceramide (d18:1/22:0) | | Synonyms: | C22 Galactosylceramide (d18:1/22:0);Docosanamide, N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-;N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-docosanamide | | CAS: | 74645-25-3 | | MF: | C46H89NO8 | | MW: | 784.2 | | EINECS: | | | Product Categories: | | | Mol File: | 74645-25-3.mol |  |
| | C22 Galactosylceramide (d18:1/22:0) Chemical Properties |
| Boiling point | 887.4±65.0 °C(Predicted) | | density | 1.03±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | A crystalline solid | | pka | 12.92±0.70(Predicted) |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | C22 Galactosylceramide (d18:1/22:0) Usage And Synthesis |
| Uses | C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients. | | Definition | ChEBI: 1-(beta-D-galactosyl)-N-behenoylsphingosine is a D-galactosyl-N-acylsphingosine where the ceramide N-acyl group is docosananoyl and the D-galactosyl component has beta anomeric configuration. It has a role as a mouse metabolite. It is functionally related to a docosanoic acid. | | Biological Activity | C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2 C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1 C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer's disease.2 [Matreya, LLC.] | | References | 1.Jové, M., Ayala, V., Ramírez-Núez, O., et al.Specific lipidome signatures in central nervous system from methionine-restricted miceJ. Proteome Res.12(6)2679-2689(2013)
2.Hejazi, L., Wong, J.W.H., Cheng, D., et al.Mass and relative elution time profiling: Two-dimensional analysis of sphingolipids in Alzheimer's disease brainsBiochem. J.438(1)165-175(2011) |
| | C22 Galactosylceramide (d18:1/22:0) Preparation Products And Raw materials |
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