Tetraethyl(1,4-butylene)bisphosphonate

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Tetraethyl(1,4-butylene)bisphosphonate Basic information
Product Name:Tetraethyl(1,4-butylene)bisphosphonate
Synonyms:TETRAETHYLBUTYLENE-1,4-DIPHOSPHONATE;TETRAETHYL BUTYLENEDIPHOSPHONATE;Tetraethylbutylene-1,4-diphosphonate,98%;Phosphonic acid, P,P'-1,4-butanediylbis-, P,P,P',P-tetraethyl ester;Phosphonic acid,1,4-butanediylbis-, tetraethyl ester (9CI);P,P,P′,P-Tetraethyl P,P′-1,4-butanediylbis[phosphonate;Diethyl P-(3-chloro-2-oxopropyl)phosphonate;1,4-bis(diethoxyphosphinyl)butane
CAS:7203-67-0
MF:C12H28O6P2
MW:330.29
EINECS:
Product Categories:
Mol File:7203-67-0.mol
Tetraethyl(1,4-butylene)bisphosphonate Structure
Tetraethyl(1,4-butylene)bisphosphonate Chemical Properties
refractive index 1.4465-1.4485
Safety Information
Safety Statements 24/25
HS Code 29310099
MSDS Information
ProviderLanguage
ACROS English
Tetraethyl(1,4-butylene)bisphosphonate Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesTetraethyl butane-1,4-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl-Chain
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Tetraethyl(1,4-butylene)bisphosphonate Preparation Products And Raw materials
Tag:Tetraethyl(1,4-butylene)bisphosphonate(7203-67-0) Related Product Information
diethyl [2-(1-naphthylamino)ethyl]phosphonate [[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt [1-[bis(hydroxymethyl)amino]ethylidene]bisphosphonic acid Tetraethyl (1,6-hexylene)bisphosphonate TETRAETHYL-1,4-BENZENEDIPHOSPHONATE Tetraethyl decamethylenediphosphonate, 98% Tetraethyl (1,8-octylene)bisphosphonate 1-Butanephosphonic acid Tetraethyl(1,4-butylene)bisphosphonate DIETHYL 1-PROPANEPHOSPHONATE PROPANE-1-PHOSPHONIC ACID DIETHYL N-BUTANEPHOSPHONATE 1,4-BUTANEDIPHOSPHONIC ACID