6-Quinoxalinecarboxylic acid

6-Quinoxalinecarboxylic acid Suppliers list

Company Name:	BeiJing Hwrk Chemicals Limted
Tel:	0757-86329057 18934348241
Email:	sales4.gd@hwrkchemical.com

Company Name:	Beijing Ouhe Technology Co., Ltd
Tel:	13552068683 13522913783
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6-Quinoxalinecarboxylic acid manufacturers

6-Quinoxalinecarboxylic acid Basic information

Product Name:	6-Quinoxalinecarboxylic acid
Synonyms:	IFLAB-BB F1716-0520;RARECHEM AM LA 0027;TIMTEC-BB SBB000185;CHINOXALIN-6-CARBONSAEURE;6-Quinoxalinecarboxylic acid, 95+%;AKOS BBS-00001971;AKOS BBS-00000436;6-Quinoxalinecarboxylic acid ,97%
CAS:	6925-00-4
MF:	C9H6N2O2
MW:	174.16
EINECS:
Product Categories:	Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Quinoxalines;Aromatics;Heterocycles;Intermediates;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines
Mol File:	6925-00-4.mol

6-Quinoxalinecarboxylic acid Chemical Properties

Melting point	224-229 °C (dec.)
Boiling point	355.1±27.0 °C(Predicted)
density	1.421±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
form	Solid
pka	3.22±0.30(Predicted)
color	Light Brown to Dark Brown
InChI	InChI=1S/C9H6N2O2/c12-9(13)6-1-2-7-8(5-6)11-4-3-10-7/h1-5H,(H,12,13)
InChIKey	JGQDBVXRYDEWGM-UHFFFAOYSA-N
SMILES	N1C2C(=CC(C(O)=O)=CC=2)N=CC=1
CAS DataBase Reference	6925-00-4(CAS DataBase Reference)

Safety Information

MSDS Information

6-Quinoxalinecarboxylic acid Usage And Synthesis

Chemical Properties	Tan Solid
Uses	6-Quinoxalinecarboxylic Acid is an intermediate used in the production of antiprotozoal agents.
Synthesis	131543-46-9 619-05-6 6925-00-4 Stage 1: The compound (CAS:131543-46-9) was reacted with 3,4-diaminobenzoic acid in a mixed solvent of ethanol and acetic acid with glyoxal at 75 °C. After completion of the reaction, the resulting suspension was cooled to 5 °C and filtered. The collected wet cake of 6-quinoxaline carboxylic acid was washed with cold ethanol and subsequently dried under vacuum at 50 °C.
References	[1] Patent: US2007/179144, 2007, A1. Location in patent: Page/Page column 5; 6 [2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 4, p. 815 - 820 [3] Patent: US2009/286797, 2009, A1. Location in patent: Page/Page column 6 [4] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 14, p. 3771 - 3774 [5] European Journal of Medicinal Chemistry, 2012, vol. 48, p. 255 - 264

6-Quinoxalinecarboxylic acid Preparation Products And Raw materials

Raw materials	Ethanol-->Sodium hydroxide-->Ethyl acetate-->Methanol-->Acetic acid-->Thionyl chloride-->Chloroform-->Isopropyl alcohol-->Glyoxal-->3,4-Diaminobenzoic acid-->Quinoxaline-6-carboxylic acid ethyl ester-->Methyl 6-quinoxalinecarboxylate-->Ethyl 3,4-diaminobenzoate-->6-Quinoxalinecarbonyl chloride-->1,2-Ethenediylbis(oxy) (9CI)-->GLYOXAL SODIUM BISULFITE
Preparation Products	Quinoxaline-6-carbaldehyde

Tag:6-Quinoxalinecarboxylic acid(6925-00-4) Related Product Information

Boronic acid, 6-quinoxalinyl- (9CI) Quinoxaline-6-carbaldehyde Methyl 6-quinoxalinecarboxylate 6-Quinoxalinecarbonitrile 6-Quinoxalinepropanoic acid, β-oxo-, ethyl ester 3-Quinolinecarboxylic acid 2-Quinoxalinecarboxylic acid L-Histidine 6-Quinoxalinecarboxylic acid 3-Hydroxy-2-quinoxalinecarboxylic acid 2,3-Dimethyl-quinoxaline-6-carboxylic acid Ethyl 2-quinoxalinecarboxylate 2-Quinoxalinecarboxylic acid, 6,7-dihydroxy- (9CI) 6-Chloro-2-quinoxalinecarboxylic acid 2-Quinoxalinecarboxylic acid methyl ester 6-Chloro-2-quinoxalinecarboxylic acid 1,4-dioxide 6,7-Dimethyl-3,4-dihydro-3-oxy-2-quinoxalinecarboxylic acid ethyl ester 6,7-Dichloro-3-(trifluoromethyl)quinoxaline-2-carboxylic acid