- 4-BROMOBENZHYDRAZIDE
-
- $1.00 / 1kg
-
2019-07-06
- CAS:5933-32-4
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
|
| | 4-BROMOBENZHYDRAZIDE Basic information |
| Product Name: | 4-BROMOBENZHYDRAZIDE | | Synonyms: | Benzoic acid, 4-bromo-, hydrazide;Benzoic acid, p-bromo-, hydrazide;4-BROMOBENZOYLHYDRAZINE;4-BROMO-BENZOIC ACID HYDRAZIDE;4-BROMOBENZOIC HYDRAZIDE;4-BROMOBENZHYDRAZIDE;4-BROMOBENZOHYDRAZIDE;JR-8894, 4-Bromobenzohydrazide, 97% | | CAS: | 5933-32-4 | | MF: | C7H7BrN2O | | MW: | 215.05 | | EINECS: | 227-681-9 | | Product Categories: | Carbonyl Compounds;Hydrazides;Organic Building Blocks;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Bromine Compounds | | Mol File: | 5933-32-4.mol |  |
| | 4-BROMOBENZHYDRAZIDE Chemical Properties |
| Melting point | 167-169°C | | density | 1.615±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | Powder | | pka | 12.09±0.10(Predicted) | | color | Light beige | | Water Solubility | Soluble in hot methanol (almost transparency). Slightly soluble in water. | | BRN | 777006 | | InChI | InChI=1S/C7H7BrN2O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,9H2,(H,10,11) | | InChIKey | UYIMBYKIIMYFPS-UHFFFAOYSA-N | | SMILES | C(NN)(=O)C1=CC=C(Br)C=C1 | | CAS DataBase Reference | 5933-32-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39-37/39 | | WGK Germany | 3 | | RTECS | DG4449250 | | HS Code | 29280000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Provider | Language |
|
ALFA
| English |
| | 4-BROMOBENZHYDRAZIDE Usage And Synthesis |
| Chemical Properties | Light beige powder | | Uses | 4-Bromobenzoic hydrazide has been used in the preparation of {2-[1-oxo-3-(4-bromophenyl)-2-propenyl]hydrazide}-4-bromobenzoic acid, {2,2-[1,4-phenylenebis(1-oxo-2-propene-3,1-diyl)]dihydrazide}-p-bromobenzoic acid and substituted period[1,2-a]pyrimidine-2,4(3H)-diones (PPMDO). | | Synthesis | To a 250 mL three-necked vial was added p-bromobenzoic acid (10.0 g, 49.75 mmol) and 100 mL
Tetrahydrofuran, then add N,N'-carbonyl diimidazole (10.45g, 64.68mmol), TLC to monitor whether the raw material reaction is complete, after the reaction is complete, slowly add 80% hydrazine hydrate (4.93g, 78.77mmol) dropwise, dropwise, stirring the reaction for about 6 h. TLC to monitor whether the raw material reaction is complete (Expanding agent: petroleum ether
/Ethyl acetate 1:1). After the reaction was completed, cooled to room temperature, concentrated under reduced pressure to remove most of the organic solvent, added about 30mL of water, pulsed at room temperature for a few moments, filtration, washed with water, resulting in a white flaky solid. After 15mL
Anhydrous ethanol recrystallization yielded 9.09 g of white solid of Intermediate 3 in 85% yield. m.p. 166-167C, consistent with literature values. |
| | 4-BROMOBENZHYDRAZIDE Preparation Products And Raw materials |
|