2-BROMO-6-FLUOROBENZOYL CHLORIDE manufacturers
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| | 2-BROMO-6-FLUOROBENZOYL CHLORIDE Basic information |
| | 2-BROMO-6-FLUOROBENZOYL CHLORIDE Chemical Properties |
| Boiling point | 236℃ | | density | 1.742 | | Fp | 97℃ | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | liquid | | color | Colourless |
| | 2-BROMO-6-FLUOROBENZOYL CHLORIDE Usage And Synthesis |
| Synthesis | General method: 2-bromo-6-fluorobenzoic acid (1.0 mmol) was mixed with excess thionyl chloride (5 mL) and reacted at reflux for 2 hours. After completion of the reaction, the excess thionyl chloride was removed by vacuum concentration to give 2-bromo-6-fluorobenzoyl chloride in quantitative yield. | | References | [1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 673 - 676 [2] Patent: EP2123644, 2009, A1. Location in patent: Page/Page column 59 [3] Journal of the American Chemical Society, 2010, vol. 132, # 32, p. 11278 - 11287 [4] Synlett, 2013, vol. 24, # 19, p. 2575 - 2580 [5] Journal of the American Chemical Society, 2017, vol. 139, # 30, p. 10228 - 10231 |
| | 2-BROMO-6-FLUOROBENZOYL CHLORIDE Preparation Products And Raw materials |
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