[2H8]-Oxcarbazepine

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[2H8]-Oxcarbazepine Basic information
Product Name:[2H8]-Oxcarbazepine
Synonyms:[2H8]-Oxcarbazepine;Oxcarbazepine D7 major;Oxcarbazepine-[d8];10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-1,2,3,4,7,8,9-d7-5-carboxamide[b,f]azepine-1,2,;D8-Oxcarbazepine;Oxcarbazepine-[D8] (Standard)
CAS:1261396-65-9
MF:C15H12N2O2
MW:252.27
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Mol File:1261396-65-9.mol
[2H8]-Oxcarbazepine Structure
[2H8]-Oxcarbazepine Chemical Properties
Safety Information
MSDS Information
[2H8]-Oxcarbazepine Usage And Synthesis
UsesOxcarbazepine-d8-1 is a deuterium of Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Oxcarbazepine-d8-1 has anti-cancer and anticonvulsant effects[2].
References[1] Ashley M Thomas, et al. Old Friends With New Faces: Are Sodium Channel Blockers the Future of Adjunct Pain Medication ManagementJ Pain. 2018 Jan;19(1):1-9. DOI:10.1016/j.jpain.2017.08.001
[2] Ching-Yi Lee,et al. The effects of antiepileptic drugs on the growth of glioblastoma cell lines. J Neurooncol. 2016 May;127(3):445-53. DOI:10.1007/s11060-016-2056-6
[2H8]-Oxcarbazepine Preparation Products And Raw materials
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