ZM223 hydrochloride manufacturers
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| | ZM223 hydrochloride Basic information |
| Product Name: | ZM223 hydrochloride | | Synonyms: | ZM223 hydrochloride;Benzamide, N-[6-[[2-[(4-aminophenyl)thio]acetyl]amino]-2-benzothiazolyl]-4-(trifluoromethyl)-, hydrochloride (1:1) | | CAS: | 2438679-27-5 | | MF: | C23H17F3N4O2S2.ClH | | MW: | 539 | | EINECS: | | | Product Categories: | | | Mol File: | 2438679-27-5.mol |  |
| | ZM223 hydrochloride Chemical Properties |
| form | Solid | | color | White to off-white |
| | ZM223 hydrochloride Usage And Synthesis |
| Uses | ZM223 hydrochloride is an orally active, potent non-covalent NEDD8 activating enzyme (NAE) inhibitor with excellent anticancer activity[1]. | | References | [1] Ma H, et al. Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening. Eur J Med Chem. 2017 Jun 16;133:174-183. DOI:10.1016/j.ejmech.2017.03.076 |
| | ZM223 hydrochloride Preparation Products And Raw materials |
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