8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)-

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8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Suppliers list
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8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- manufacturers
8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Basic information
Product Name:8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)-
Synonyms:8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)-;NC9;NC9 TG2 inhibitor;NC-9 TG2 inhibitor;N-alpha-Carbobenzyloxy-N-epsilon-acryloyl-L-lysine(2-(2-dansylaminoethoxy)ethoxy)ethanamide
CAS:1352090-52-8
MF:C35H47N5O8S
MW:697.84
EINECS:
Product Categories:
Mol File:1352090-52-8.mol
8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Structure
8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Chemical Properties
density 1.225±0.06 g/cm3(Predicted)
pka10.99±0.50(Predicted)
Safety Information
MSDS Information
8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Usage And Synthesis
DescriptionNC9 is a irreversible transglutaminase 2 (TG2) inhibitor. NC9 also inhibits Factor XIIIA (FXIIIA).
UsesNC9 (Cbz-Lys(Acr)-PEG2-dansyl) is an irreversible transglutaminase (TG) inhibitor. NC9 inhibits osteoblast differentiation and mineralization. NC9 destabilizes microtubules. NC9 can be used for the research of osteoblast differentiation[1].
References[1] Al-Jallad HF, et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. PLoS One. 2011 Jan 20;6(1):e15893. DOI:10.1371/journal.pone.0015893
8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)- Preparation Products And Raw materials
Tag:8,11-Dioxa-2,5-diazatridecanoic acid, 13-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]-4-oxo-3-[4-[(1-oxo-2-propen-1-yl)amino]butyl]-, phenylmethyl ester, (3S)-(1352090-52-8) Related Product Information
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