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| | (3beta,24S)-stigmast-5-en-3-ol Basic information |
| Product Name: | (3beta,24S)-stigmast-5-en-3-ol | | Synonyms: | (3beta,24S)-stigmast-5-en-3-ol;(3b,24S)-stigmast-5-en-3-ol;(24S)-Stigmast-5-en-3β-ol;22,23-Dihydroporiferasterol;beta-Dihydrofucosterol;Einecs 201-481-1;Stigmast-5-en-3-ol, (3β,24S)-;Stigmast-5-en-3-ol, (3b,24S)- | | CAS: | 83-47-6 | | MF: | C29H50O | | MW: | 414.71 | | EINECS: | 201-481-1 | | Product Categories: | | | Mol File: | 83-47-6.mol |  |
| | (3beta,24S)-stigmast-5-en-3-ol Chemical Properties |
| Boiling point | 473.52°C (rough estimate) | | density | 0.9540 (rough estimate) | | refractive index | 1.5000 (estimate) | | Melting point | 147 °C | | pKa | 15.03±0.70(Predicted) |
| | (3beta,24S)-stigmast-5-en-3-ol Usage And Synthesis |
| Uses | γ-Sitosterol is an inhibitor for c-Myc. γ-Sitosterol inhibits the proliferation of cancer cell MCF-7 and A549 with IC50 of 240.73 μg/mL and 696.6 μg/mL, arrests the cell cycle at G2/M phase, and induces apoptosis. γ-Sitosterol upregulates the expression of cell cycle regulators cyclin B/E[1]. | | Definition | ChEBI: Clionasterol is a member of the class of phytosterols that is poriferast-5-ene carrying a beta-hydroxy substituent at position 3. It has a role as a plant metabolite and a marine metabolite. It is a 3beta-sterol, a member of phytosterols and a 3beta-hydroxy-Delta(5)-steroid. It derives from a hydride of a poriferastane. | | References | [1] Sundarraj S, et al., γ-Sitosterol from Acacia nilotica L. induces G2/M cell cycle arrest and apoptosis through c-Myc suppression in MCF-7 and A549 cells. J Ethnopharmacol. 2012 Jun 14;141(3):803-9. DOI:10.1016/j.jep.2012.03.014 |
| | (3beta,24S)-stigmast-5-en-3-ol Preparation Products And Raw materials |
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