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| | 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Basic information |
| Product Name: | 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol | | Synonyms: | 1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol;1,2,5-Thiadiazole, 2-propanol deriv.;2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]- (8CI);2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]- (9CI);Racemic timolol;(+/-)-Timolol-d5 Maleate;1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol-d5 Maleate;3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole-d5 Maleate | | CAS: | 29023-48-1 | | MF: | C13H24N4O3S | | MW: | 316.42 | | EINECS: | 249-374-9 | | Product Categories: | Amines;Heterocycles;Isotope Labelled Compounds;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals | | Mol File: | 29023-48-1.mol | ![1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Structure](CAS/GIF/29023-48-1.gif) |
| | 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Chemical Properties |
| Melting point | 210-212°C | | Boiling point | 487.2±45.0 °C(Predicted) | | density | 1.224±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.38±0.20(Predicted) | | color | White |
| | 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent | | Uses | rac Timolol Maleate is an antihypertensive and antiarrhythmic. It can be used to treat hemangioma and vascular anomaly. | | Definition | ChEBI: Timolol is 1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine. It is a member of thiadiazoles and a member of morpholines. It derives from a hydride of a 1,2,5-thiadiazole. |
| | 1-(tert-butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol Preparation Products And Raw materials |
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