| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
PALMITOYL CARNITINE manufacturers
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| | PALMITOYL CARNITINE Basic information |
| Product Name: | PALMITOYL CARNITINE | | Synonyms: | (-)-[(R)-3-Carboxylato-2-(palmitoyloxy)propyl]trimethylaminium;(2R)-3-Carboxylato-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium;Palmitoyl L-carnitine;Palmitylcarnitine;C02990;1-PropanaMiniuM, 3-carboxy-N,N,N-triMethyl-2-[(1-oxohexadecyl)oxy]-, inner salt, (2R)-;O-palmitoyl-L-carnitine;(3R)-3-hexadecanoyloxy-4-trimethylazaniumylbutanoate | | CAS: | 2364-67-2 | | MF: | C23H45NO4 | | MW: | 399.61 | | EINECS: | | | Product Categories: | | | Mol File: | 2364-67-2.mol |  |
| | PALMITOYL CARNITINE Chemical Properties |
| storage temp. | 2-8°C | | solubility | Soluble in DMSO | | form | liquid | | pka | 3.389±0.10(predicted) | | color | White to off-white | | Optical Rotation | [α]/D -17±2°, c = 1 in methanol | | BRN | 4152034 | | Major Application | clinical testing | | Cosmetics Ingredients Functions | SKIN CONDITIONING | | InChI | 1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1 | | InChIKey | XOMRRQXKHMYMOC-OAQYLSRUSA-N | | SMILES | C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | PALMITOYL CARNITINE Usage And Synthesis |
| Uses | L-Palmitoyl Carnitine is used as a diagnostic agent in the investigation of drug toxicity with respect to the liver. Acts as a biomarker in the study of metabolism in metabolic diseases. | | Definition | ChEBI: An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl). | | General Description | Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts. | | Biochem/physiol Actions | L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics. | | IC 50 | Kir6.2; Human Endogenous Metabolite |
| | PALMITOYL CARNITINE Preparation Products And Raw materials |
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