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Methyl palmitate

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CAS:112-39-0
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Methyl palmitate manufacturers

  • Methyl palmitate
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  • $44.00 / 1kg
  • 2026-03-09
  • CAS:112-39-0
  • Min. Order: 1kg
  • Purity: 0.98
  • Supply Ability: 100kg
  • Methyl palmitate
  • Methyl palmitate pictures
  • $0.00 / 180Kg/Drum
  • 2026-03-09
  • CAS:112-39-0
  • Min. Order: 180KG
  • Purity: 98%min
  • Supply Ability: 250tons/month
  • Methyl palmitate
  • Methyl palmitate pictures
  • $10.00 / 25kg
  • 2026-03-06
  • CAS:112-39-0
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Methyl palmitate Basic information
Product Name:Methyl palmitate
Synonyms:PALMITIC ACID METHYL ESTER;METHYL PALMITATE, STANDARD FOR GC;Emery 2216;Metholene 2216;metholene2216;n-Hexadecanoic acid methyl ester;METHYL PALMITATE 97+%;METHYL PALMITATE, 99+%
CAS:112-39-0
MF:C17H34O2
MW:270.45
EINECS:203-966-3
Product Categories:Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives;Analytical Chemistry;Fatty Acid Methyl Esters (GC Standard);Standard Materials for GC;bc0001
Mol File:112-39-0.mol
Methyl palmitate Structure
Methyl palmitate Chemical Properties
Melting point 32-35 °C (lit.)
Boiling point 185 °C/10 mmHg (lit.)
density 0.852 g/mL at 25 °C (lit.)
vapor pressure 0.008Pa at 25℃
refractive index n20/D 1.4512(lit.)
Fp >230 °F
storage temp. 2-8°C
solubility Chloroform (Sparingly), Methanol (Slightly)
form Liquid or Low Melting Solid
color Clear colorless
Specific Gravity0.852
Odorat 100.00 %. oily waxy fatty orris
Odor Typewaxy
biological sourceplant (palm)
Water Solubility INSOLUBLE
BRN 1780973
Cosmetics Ingredients FunctionsSKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT
PERFUMING
InChI1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3
InChIKeyFLIACVVOZYBSBS-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCCCC(=O)OC
LogP7.38 at 36℃
CAS DataBase Reference112-39-0(CAS DataBase Reference)
NIST Chemistry ReferenceHexadecanoic acid, methyl ester(112-39-0)
EPA Substance Registry SystemMethyl palmitate (112-39-0)
Safety Information
Safety Statements 22-24/25
WGK Germany 1
TSCA TSCA listed
HS Code 29157090
Storage Class11 - Combustible Solids
Hazardous Substances Data112-39-0(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Methyl hexadecanoate English
ACROS English
SigmaAldrich English
ALFA English
Methyl palmitate Usage And Synthesis
Chemical PropertiesClear colorless liquid or low melting solid. Soluble in alcohol, acetone, chloroform and benzene, soluble in ether, insoluble in water.
UsesMethyl palmitate is used in the preparation of detergents, emulsifiers, wetting agents, stabilizers, resins, lubricants, plasticizers and animal feeds. It exhibits an anti-inflammatory and anti-fibrotic agent and prevents bleomycin-induced lung inflammation and fibrosis in rats. In addition, it also prevents carbon tetrachloride-induced liver fibrosis linked to reduce transforming growth factor beta, which is a secreted protein that controls proliferation, cellular differentiation and other functions in most cells.
UsesMethyl palmitate can be used as an additive in food and cosmetic industries for the stabilization of fats and oil products by slowing down the auto-oxidation of unsaturated fatty acids.
ApplicationMethyl Palmitate is a fatty acid ester essential oil that naturally occurs in many plant species. Methyl Palmitate concentration in cells are known to be modulated by methanol. In experimental studies with isolated Kupffer cells, Methyl palmitate exhibited inhibitory activity towards phagocytosis and decreases cell viability.
DefinitionChEBI: Methyl palmitate is a fatty acid methyl ester. It has a role as a metabolite.
Biological FunctionsSaturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long- term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake, and approximately 25% of the total plasma fatty acids in plasma lipoproteins. Saturated free fatty acids induce the expression of cyclooxygenase-2. Palmitic acid methyl ester (MP) is a fatty acid ester whose concentration in cells is modulated by methanol. In studies with isolated Kupffer cells, MP inhibits phagocytosis and decreases cell viability. In cells treated with lipopolysaccharide, it also decreases secretion of interleukin-10, TNF-α, nitric oxide, and prostaglandin E2. This effect is thought to occur by the inhibition of NF-κB.
Synthesis Reference(s)Synthetic Communications, 16, p. 1423, 1986 DOI: 10.1080/00397918608056391
General DescriptionMethyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.
Flammability and ExplosibilityNon flammable
Biochem/physiol ActionsMethyl palmitate has anti-inflammatory and anti-fibrotic effect. Methyl palmitate prevents bleomycin-induced lung inflammation and fibrosis in rats, by inhibiting NF-κB . Methyl palmitate also prevents CCl4-induced liver fibrosis linked to reduced TGF-β .
SynthesisAt present, there are two main methods to obtain methyl palmitate, one is to prepare fatty acid methyl ester mixture by transesterification reaction between palm oil and methanol under alkaline catalytic condition, which is used for biodiesel; the other one is to use concentrated sulfuric acid as the catalyst, and palm acid and methanol are directly dehydrated and esterified to prepare methyl palmitate. In the direct esterification method, concentrated sulfuric acid corrodes the equipment seriously, the product is not easy to separate, the post-treatment process is complicated, and the wastewater causes serious pollution to the environment, and the strong oxidizing property of concentrated sulfuric acid can easily cause the product to deepen in color in the reaction process.
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