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[Des-Tyr1]Retatrutide
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H-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Phe6]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-AEEA]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Phe22]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Gln3]Retatrutide
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H-Tyr1-Aib2-Gln3-Gln-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ser8]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Ser-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Tyr25]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Tyr-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ser32]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double His1]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-D-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Glu15]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-D-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Phe22]Semaglutide
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[D-Thr5]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-D-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ile12]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-D-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Gln24]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-D-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Thr5]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Gly34]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Thr7]Semaglutide
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H-His1-Aib2-Glu3-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Gly4]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Glu15]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Side Chain]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des γE]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Phe-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Thr7]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Trp-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Leu26]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-Gly-OH
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[Double AEEA]Semaglutide
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[D-Ala28]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-D-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-γ-Glu]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-D-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ala18]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des AEEA(Side Chain)]-Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ala35]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Glu3]Tirzepatide
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H-Tyr1-Aib2-Glu3-Glu-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Gln19]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Gln-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Gln24]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Gln-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Glu24]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Glu24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Gln3]Retatrutide
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H-Tyr1-Aib2-D-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Gln19]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-D-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Tyr25]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-D-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ser33]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-D-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Allo-Thr7]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-D-Allo-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Gln3]Retatrutide
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H-Tyr1-Aib2-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Lys17(Side Chain)]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Gln19]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ser39]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-NH2
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[Double-Thr5]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Thr-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Phe22]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Phe-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Glu28]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Glu-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-D-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Ala19]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-D-β-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Val10]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-D-Arg30-Gly31-0H
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[α-Glu](Side Chain)-Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-β-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-β-Asp9]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Ser12]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Gln17]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Arg30-Gly31-OH
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[Des Arg30]Semaglutide
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H-His1-His-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Glu3]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Phe-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Ile23]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Val-Arg28-Gly29-Arg30-Gly31-OH
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[Double Gly29]Semaglutide
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[D-Val23]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-D-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Pro36]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-D-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Leu14]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Gln19]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ile27-Ala28]-Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Pro36-Pro37]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Lys16]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Lys-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Ala21]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Ala-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Acetylated]Tirzepatide
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Ac-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[α-Glu](Side Chain)Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Lys16]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-D-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Phe22]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-D-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[β-Asp9]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-β-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[γ-Glu28]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-γ-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Tyr10]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Asp15]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Leu26]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Gly34]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ile12]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Ile-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ala18]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Ala-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ser39]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-Ser-NH2
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[Fragment-Pyr3-39]Retatrutide
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Pyr3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-(D-Allo-Thr5)-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Phe6]Semaglutide
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[D-Ser11]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-D-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des-His1-Aib2]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Asp9]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Ile23]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Arg28-Gly29-Arg30-Gly31-OH
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[Des Arg28]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Val-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Ser11]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Gln-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Ala18]Semaglutide
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Ac-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Ile17]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-D-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Glu3]Tirzepatide
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H-Tyr1-Aib2-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ser11]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Val23]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ala28]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Thr7]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Thr-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double -Ile12]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12--Ile-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Ala28]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Ala-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Ala35]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Ala-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ser8]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-D-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-(α)MeLeu13]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-D-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Pro31]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-D-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Pro38]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-D-Pro38-Ser39-NH2
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[Des-Aib2]Retatrutide
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H-Tyr1-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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