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[Des-Thr7]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ala18]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ile23]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Gly4]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Gly-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Asp9]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Asp-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Leu26]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Gly34]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Gly-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Tyr10]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-D-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Glu21]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-D-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Ser11]Semaglutide
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[D-Ser39]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-D-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-(D-Allo-Ile23)-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Ala24]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-D-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Asp9]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-D-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Val27]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Tyr13]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Ala18]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Gly31-OH
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[Des (Arg30 Gly31)]Semaglutide
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H-His1-Aib2-Glu3-Glu-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Gly4]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ile-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Ala24]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Gly-Arg30-Gly31-OH
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[Double Arg30]Semaglutide
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[D-Trp25]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-D-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Pro37]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-D-Pro37-Pro38-Ser39-NH2
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[Des Asp15]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Side Chain]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Gly29-Gly30]-Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Ser39]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-NH2
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[Double Ile17]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ile-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Phe22]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Phe-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Nva12]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Nva12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Trp(O)25]Tirzepatide
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H-Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys(AEEA-AEEA-γ-Glu-C20-diacid)-Ala-Phe-Val-Gln-{S'-Trp(O)}-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
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[D--Lys17]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-D-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ile23]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-D-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-β-Asp15]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-D-β-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[α-Glu](Side Chain)Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-α-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ser11]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Lys16]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Glu28]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ala35]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Leu14]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Leu-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Gln19]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Gln-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Ser39-OH]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Fragment-Pyr28-39]Retatrutide
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Pyr28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Asp9]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-D-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Gln19]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-D-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ser32]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-D-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Leu14]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-D-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-(D-Allo-Thr7)-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Thr7]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Gly16]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Lys20(Side Chain)]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Oct]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Thr-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Ser8]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Leu-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Val27]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Glu17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Trp25(O)]Semaglutide
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[D-Ala35]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-D-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Tyr1~Gly4]Tirzepatide
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H-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Thr7]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des γ-Glu(Side Chain)]-Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Trp25]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Gly4]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Gly-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Asp9]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Asp-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Trp25]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Trp-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Pro31]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Pro-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Thr5]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-D-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Tyr10]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-D-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Leu26]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-D-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ala35]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-D-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Allo-Ile12]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-D-Allo-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Gly4]Retatrutide
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H-Tyr1-Aib2-Gln3-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Eicosanedioicacid]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Aib20]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Gly29-Gly30]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Phe6]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Phe-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Ile23]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Ile-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double-Gly29]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Tyr1]Tirzepatide
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H-D-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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H-His1-Aib2-Glu3-Gly4-D-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Allo-Thr5]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-D-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[D-Trp25]Semaglutide
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H-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des-Aib2]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Val10]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Des Ala24]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Gly29-Arg30-Gly31-OH
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[Des (Arg28 Gly31]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Tyr13]Semaglutide
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H-His1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Val10-Ser11-Ser12-Tyr13-Leu14-Glu15-Gly16-Gln17-Ala18-Ala-Ala19-Lys20(AEEA-AEEA-γ-Glu-Oct)-Glu21-Phe22-Ile23-Ala24-Trp25-Leu26-Val27-Arg28-Gly29-Arg30-Gly31-OH
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[Double Glu21]Semaglutide
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[D-Thr7]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-D-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Lys20]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-D-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des- Glu3-Gly4]Tirzepatide
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H-Tyr1-Aib2-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Aib13]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Gln24]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des Gly29]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Ser8]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Ser-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Leu14]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Leu-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Gly29]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Double Pro36]Tirzepatide
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H-Tyr1-Aib2-Glu3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Aib13-Leu14-Asp15-Lys16-Ile17-Ala18-Gln19-Lys20(AEEA-AEEA-γ-Glu-C20-diacid)-Ala21-Phe22-Val23-Gln24-Trp25-Leu26-Ile27-Ala28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro-Pro37-Pro38-Ser39-NH2
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[D-Asp9]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-D-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Leu14]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-D-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ser32]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-D-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[D-Ser39]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-D-Ser39-NH2
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[D-γ-Glu]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-D-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-Ser8]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Asp9-Tyr10-Ser11-Ile12-(α)MeLeu13-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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[Des-(α)MeLeu13]Retatrutide
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H-Tyr1-Aib2-Gln3-Gly4-Thr5-Phe6-Thr7-Ser8-Asp9-Tyr10-Ser11-Ile12-Leu14-Asp15-Lys16-Lys17(Eicosanedioicacid-γ-Glu-AEEA)-Ala18-Gln19-Aib20-Ala21-Phe22-Ile23-Glu24-Tyr25-Leu26-Leu27-Glu28-Gly29-Gly30-Pro31-Ser32-Ser33-Gly34-Ala35-Pro36-Pro37-Pro38-Ser39-NH2
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