长沙上禾生物科技有限公司
Changcha Sunho Biotech Co., Ltd
公司简介 | Company Profile
长沙上禾生物科技有限公司是一家专注于高活性天然异黄酮类化合物研发、生产与销售的国家高新技术企业。公司以现代植物化学、内分泌药理学与骨骼健康科学为核心，构建了从特色豆科植物资源筛选、高纯度单体定向制备到雌激素受体调节作用机制系统研究的全产业链技术平台。我们致力于为全球骨骼健康、女性健康、心血管保护及功能性食品行业提供高效、安全、标准化的天然植物雌激素原料，尤其在“刺芒柄花素”这一选择性雌激素受体调节剂开发与应用领域，构筑了领先的技术优势。
Changcha Sunho Bio-Tech Co., Ltd. is a national high-tech enterprise specializing in the R&D, production, and sales of highly active natural isoflavone compounds. With modern phytochemistry, endocrine pharmacology, and bone health science as its core, the company has built a full industrial chain technology platform spanning from the screening of characteristic leguminous plant resources, targeted preparation of high-purity monomers, to systematic research on estrogen receptor modulation mechanisms. We are committed to providing efficient, safe, and standardized natural phytoestrogen raw materials for the global bone health, women's health, cardiovascular protection, and functional food industries. We have established leading technological advantages, particularly in the development and application of the selective estrogen receptor modulator "Formononetin."
核心来源 | Core Source:
主要从豆科植物黄芪（Astragalus membranaceus）、红三叶草（Trifolium pratense）、葛根（Pueraria lobata）等植物中，通过现代提取与色谱分离技术制备高纯度刺芒柄花素。
Sourced primarily from leguminous plants such as Astragalus membranaceus, Red Clover (Trifolium pratense), and Kudzu (Pueraria lobata), high-purity formononetin is prepared through modern extraction and chromatographic separation techniques.
主打产品：刺芒柄花素 | Core Product: Formononetin
产品概述 | Product Overview
刺芒柄花素 是一种广泛存在于多种豆科植物中的天然异黄酮类化合物。它作为植物雌激素的一种，具有温和的雌激素样活性，但其作用特点在于对雌激素受体β表现出较高的选择性亲和力。这种选择性使其能够模拟雌激素在某些组织（如骨骼、心血管系统）的有益作用，同时避免或减少在乳腺、子宫等组织可能产生的过度刺激风险。刺芒柄花素以其促进成骨细胞活性、抑制破骨细胞生成（保护骨骼）、改善血脂代谢、抗氧化、抗炎、舒张血管等生物活性而受到广泛关注。在应对绝经后骨质疏松、动脉粥样硬化、更年期综合症相关症状等方面展现出应用潜力，被视为一种有前景的选择性雌激素受体调节剂。
Formononetin is a natural isoflavone compound widely found in various leguminous plants. As a type of phytoestrogen, it possesses mild estrogen-like activity, but its characteristic lies in its relatively high selective affinity for estrogen receptor beta. This selectivity allows it to mimic the beneficial effects of estrogen in certain tissues (such as bones, cardiovascular system) while avoiding or reducing the potential risk of overstimulation in tissues like breast and uterus. Formononetin has attracted widespread attention for its biological activities, including promoting osteoblast activity, inhibiting osteoclast formation (bone protection), improving lipid metabolism, antioxidant, anti-inflammatory, and vasodilatory effects. It shows application potential in addressing postmenopausal osteoporosis, atherosclerosis, and menopausal syndrome-related symptoms, and is regarded as a promising selective estrogen receptor modulator.
产品规格 | Product Specifications
项目 Parameter | 规格标准 Specification | 7-羟基-4'-甲氧基异黄酮 7-Hydroxy-4'-methoxyisoflavone
白色至淡黄色结晶性粉末或粉末 White to light yellow crystalline powder or powder
符合HPLC, IR, MS, NMR等标准方法 Complies with standard methods like HPLC, IR, MS, NMR
≥ 95.0%, 98.0%, 99.0%, 99.5% (可按客户要求定制) ≥ 95.0%, 98.0%, 99.0%, 99.5% (Customizable per client requirements)
严格控制大豆苷元、染料木素、鹰嘴豆芽素A等其他异黄酮杂质 Strictly control other isoflavone impurities like daidzein, genistein, biochanin A
符合ICH Q3C要求 Complies with ICH Q3C requirements
符合非无菌原料药/食品原料要求 Complies with requirements for non-sterile APIs/food ingredients
几乎不溶于水， 溶于DMSO、DMF、吡啶、稀碱溶液， 微溶于甲醇、乙醇、丙酮。 Practically insoluble in water; soluble in DMSO, DMF, pyridine, dilute alkaline solutions; slightly soluble in methanol, ethanol, acetone.
1kg/5kg/10kg/25kg铝箔袋 (标准品) 或 1g/5g/10g/25g/50g/100g 棕色玻璃瓶 (高纯/科研级)， 内充惰性气体， 外用避光容器 1kg/5kg/10kg/25kg aluminum foil bag (standard grade) or 1g/5g/10g/25g/50g/100g amber glass vial (high-purity/research grade), filled with inert gas, outer light-proof container
密封， 避光， 在阴凉干燥处保存。 建议低温冷藏以保持长期稳定。 Keep tightly sealed, protected from light, in a cool, dry place. Low-temperature refrigeration is recommended for long-term stability.
主要应用领域 | Main Application Fields
骨骼健康与更年期支持产品 | Bone Health and Menopause Support Products
预防与改善骨质疏松：作为核心成分，用于增加骨密度、预防绝经后骨质疏松、改善骨骼健康的膳食补充剂，尤其适合对传统激素疗法有顾虑的女性。
Preventing and Improving Osteoporosis: As a core ingredient, used in dietary supplements for increasing bone mineral density, preventing postmenopausal osteoporosis, and improving bone health, particularly suitable for women concerned about traditional hormone therapy.
缓解更年期症状：用于辅助缓解潮热、盗汗、情绪波动等更年期相关症状。
Alleviating Menopausal Symptoms: Used to assist in alleviating menopausal-related symptoms such as hot flashes, night sweats, and mood swings.
心血管健康产品 | Cardiovascular Health Products
保护心血管：通过改善血脂谱、抗氧化、抗炎、舒张血管，用于支持心血管健康、预防动脉粥样硬化。
Cardiovascular Protection: Through improving lipid profile, antioxidant, anti-inflammatory, and vasodilatory effects, used to support cardiovascular health and prevent atherosclerosis.
女性健康与内分泌调节产品 | Women's Health and Endocrine Regulation Products
温和内分泌调节：作为植物性选择性雌激素受体调节剂，用于支持女性内分泌系统平稳过渡（如围绝经期）、改善皮肤健康、维持活力。
Mild Endocrine Regulation: As a phyto-selective estrogen receptor modulator, used to support a smooth transition of the female endocrine system (e.g., perimenopause), improve skin health, and maintain vitality.
抗炎与抗氧化产品 | Anti-inflammatory and Antioxidant Products
全身抗氧化与抗炎：作为抗氧化和抗炎成分，用于延缓衰老、保护细胞免受氧化损伤、减轻慢性低度炎症。
Systemic Antioxidant and Anti-inflammatory: As an antioxidant and anti-inflammatory ingredient, used for delaying aging, protecting cells from oxidative damage, and reducing chronic low-grade inflammation.
科研与新药开发 | Scientific Research and New Drug Development
SERM研究工具：作为选择性雌激素受体调节剂研究的重要工具分子，用于相关受体结合、信号通路、疾病模型的研究。
SERM Research Tool: As an important tool molecule for research on selective estrogen receptor modulators, used in studies related to receptor binding, signaling pathways, and disease models.
我们的核心优势 | Our Core Advantages
“高纯度刺芒柄花素单体”规模化制备专家：我们从富含异黄酮的豆科植物中高效分离与纯化刺芒柄花素，确保其高化学纯度。我们采用先进的色谱分离与结晶纯化工艺，能够稳定提供纯度高达95%-99.5% 的刺芒柄花素单体，并严格控制其他异黄酮类杂质的含量，满足高端科研及健康产品对原料纯度的严格要求。
“选择性雌激素受体β激动剂”的科学定位者：我们深度聚焦并科学阐释刺芒柄花素的核心特征——对雌激素受体β的选择性亲和。我们系统梳理其通过激活ERβ介导的促进成骨、抑制破骨、改善血脂、保护心血管等有益作用，同时强调其对ERα作用较弱，从而可能具有更好的组织选择性与安全性特征。我们将其定位为“骨骼与心血管友好的植物雌激素”，科学支撑其在骨骼健康与心血管保护领域的差异化应用价值。
“骨骼健康与心血管保护双效合一”的创新应用开拓者：我们系统整合刺芒柄花素在促进骨形成、抑制骨吸收以及改善血脂、抗动脉粥样硬化两大领域的科学证据。我们将其打造为“针对绝经后女性健康的双重天然支持者”，可同时应用于预防骨质疏松和支持心血管健康的产品开发，为这一人群提供综合健康解决方案。
“传统草本智慧的现代科学诠释”：我们巧妙地将刺芒柄花素来源植物（如黄芪、红三叶草）在传统应用中的“补气、利水、通脉”等功效，科学转化为其雌激素样活性带来的骨骼、心血管及整体健康益处的现代生物学语言。我们将其打造为“源自传统豆科植物的现代选择性健康调节剂”，实现了传统认知与现代科学的有效链接。
“科研与产业化的桥梁”：刺芒柄花素因其明确的作用靶点，已成为内分泌、骨骼、心血管研究领域的重要工具分子。我们为基础科研、新药发现提供高纯度试剂。同时，我们积极推动其基于循证证据的产业化应用，为开发面向更年期女性及骨骼健康需求人群的功能性食品和膳食补充剂提供可靠的原料和科学背书。
包装与储存 | Packaging & Storage
内包装：铝箔袋（标准品）或棕色玻璃瓶（高纯/科研级），充氮保护，严格密封避光。
Inner Packaging: Aluminum foil bag (standard grade) or amber glass vial (high-purity/research grade), nitrogen-filled for protection, tightly sealed and light-protected.
外包装：外用避光容器。
Outer Packaging: External light-proof container.
储存条件：密闭，避光，在阴凉、干燥处保存。长期储存建议低温冷藏。
Storage Conditions: Keep tightly closed, protected from light, in a cool, dry place. Low-temperature refrigeration is recommended for long-term storage.
联系我们 | Contact Us
长沙上禾生物科技有限公司
Charissa Liu
E-mail：sales05@staherb.cn sales@staherb.cn
Whatsapp:+86-13657431735
Wechat:+86-13657431735
公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证
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